Results 81 to 90 of about 649,794 (306)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
CPAS Preflight Drop Test Analysis Process [PDF]
, 2015 Throughout the Capsule Parachute Assembly System (CPAS) drop test program, the CPAS Analysis Team has developed a simulation and analysis process to support drop test planning and execution.
Bledsoe, Kristin J. +2 more
core +1 more source
Verfahrensdokumentation für STSE: Scale for Teacher Self-Efficacy - deutsche adaptierte Fassung [PDF]
, 2016 Die STSE ist die deutsche Adaptation der Teacher's Sense of Efficacy Scale (TSES; Tschannen-Moran & Woolfolk Hoy, 2001) und wird zur Erfassung der Lehrer-Selbstwirksamkeit eingesetzt. Sie umfasst drei Skalen mit je 4 Items: (1) Instruktionsstrategien, (2)
Pfitzner-Eden, F.
core +1 more source
An FBG-Based Hard Landing Monitoring System: Assessment for Drops on Different Soils
PhotonicsThis study aims to develop an integrated monitoring system using a fiber Bragg grating sensor network to record the structural response of a landing gear system under operational loads to detect hard landing conditions on soils with different absorbing ...
Angela Brindisi +6 more
doaj +1 more source
ANALISIS KOMPONEN WAKTU REAKSI ATLET BULUTANGKIS (STUDI PADA ATLET BULUTANGKIS DI SEMARANG)
Jurnal Kedokteran Diponegoro, 2017 Latar Belakang: Latihan rutin yang dilakukan oleh para atlet bulutangkis akan meningkatkan komponen fisik yaitu kecepatan yang ditunjukkan melalui waktu reaksi.
Amitya Ekacitta Anindita +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The 2008 Dutch NRL/IAG proficiency test for detection of animal proteins in feed [PDF]
, 2008 The results of a proficiency test for the detection of animal proteins in animal feed by microscopy, PCR (DNA detection) and immunoassay methods are presented in this ...
Pinckaers, V.G.Z. +5 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source