Results 31 to 40 of about 5,995,584 (403)
A Protein Complex Network of Drosophila melanogaster [PDF]
Cell, 2011 Determining the composition of protein complexes is an essential step toward understanding the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry analysis, we examined protein associations involving nearly 5,000 individual, FLAG-HA epitope-tagged Drosophila proteins.
Julian Mintseris +23 more
openaire +3 more sources
Cross-Species Interaction between Rapidly Evolving Telomere-Specific Drosophila Proteins. [PDF]
PLoS ONE, 2015 Telomere integrity in Drosophila melanogaster is maintained by a putative multisubunit complex called terminin that is believed to act in analogy to the mammalian shelterin complex in protecting chromosome ends from being recognized as sites of DNA ...
Balázs Vedelek +2 more
doaj +1 more source
Analysis of Thisbe and Pyramus functional domains reveals evidence for cleavage of Drosophila FGFs [PDF]
, 2010 Background: As important regulators of developmental and adult processes in metazoans, Fibroblast Growth Factor (FGF) proteins are potent signaling molecules whose activities must be tightly regulated.
Stathopoulos, Angelike, Tulin, Sarah
core +4 more sources
Regulation of alternative splicing in Drosophila by 56 RNA binding proteins
Genome Research, 2015 Alternative splicing is regulated by RNA binding proteins (RBPs) that recognize pre-mRNA sequence elements and activate or repress adjacent exons. Here, we used RNA interference and RNA-seq to identify splicing events regulated by 56 Drosophila proteins,
Angela N. Brooks +11 more
semanticscholar +1 more source
PROTEIN DIFFERENCES IN DROSOPHILA. I. DROSOPHILA MELANOGASTER [PDF]
Genetics, 1963 ONE electrophoresis affords a simple, rapid technique for comparing and characterizing proteins. It is especially suitable for investigations of genetically altered proteins, and notable results have come from the use of this method in studying hemoglobins (INGRAM 1961 ) and haptoglobins ( CONNELL, DIXON and SMITHIES 1962).
openaire +3 more sources
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
The distribution of GYR- and YLP-like motifs in Drosophila suggests a general role in cuticle assembly and other protein-protein interactions. [PDF]
PLoS ONE, 2010 BACKGROUND: Arthropod cuticle is composed predominantly of a self-assembling matrix of chitin and protein. Genes encoding structural cuticular proteins are remarkably abundant in arthropod genomes, yet there has been no systematic survey of conserved ...
R Scott Cornman
doaj +1 more source
Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 [PDF]
, 2002 The toxicity of an abnormally long polyglutamine [poly(Q)] tract within specific proteins is the molecular lesion shared by Huntington's disease (HD) and several other hereditary neurodegenerative disorders.
Benzer, Seymour, Kazemi-Esfarjani, Parsa
core +1 more source
Drosophila Mechanotransduction—Linking Proteins and Functions [PDF]
Fly, 2007 The sensation of touch, gravity, and sound all rely on dedicated ion channels that transduce mechanical stimulus forces into electrical signals. The functional workings and molecular identities of these mechanotransducer channels are little understood. Recent work shows that the mechanotransducers for fly and vertebrate hearing share equivalent gating ...
Albert, Jörg T. +2 more
openaire +4 more sources
Informatics in Medicine Unlocked, 2022 Claudins are a class of transmembrane proteins in the family of tight junction (TJ) proteins. The disrupted functioning of claudins has been found to have a role in urolithiasis (Kidney stones).
Anirudh Gururaj Patil +4 more
doaj