Results 91 to 100 of about 2,208,548 (262)
Drug–drug interaction analysis: Antituberculosis drugs versus antiretroviral drugs
Biomedical and Biotechnology Research Journal, 2019 Background: Human immunodeficiency virus (HIV) infection is an important public health globally. An important concomitant medical disorder among HIV-infected patients is tuberculosis. The management of concurrent infection between HIV and tuberculosis is
Won Sriwijitalai, Viroj Wiwanitkit
doaj +1 more source
Systematic Exploration of Synergistic Drug Pairs [PDF]
, 2013 Drug synergy allows a therapeutic effect to be achieved with lower doses of component drugs. Drug synergy can result when drugs target the products of genes that act in parallel pathways (‘specific synergy’).
Andrews, Brenda J +14 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A study of the impact of grapefruit-drug interaction on the demand for grapefruit juice [PDF]
grapefruit juice, drug interaction, demand, Agribusiness, Demand and Price Analysis,
Brown, Mark G., Lee, Jonq-Ying
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Clozapine treatment in patients living in the community [PDF]
, 2015 OBJECTIVE: The aim of this study was to assess clozapine treatment in the local community with respect to patient monitoring during dispensing, patient compliance through prescription refills, presence of any other existing co-morbidities and ...
Azzopardi, Lilian M., Schembri, Karl
core
A simple molecular modeling method for the characterization of polymeric drug carriers [PDF]
, 2013 A simple molecular modeling method for the characterization of polymeric drug carriers is presented. Six biodegradable polymers have been investigated as drug carriers using molecular simulations: l-polylactide, d-polylactide, chitosan, polyglycolic acid,
Macháčková, Miroslava +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Drug-Drug Interaction Management in Hepatitis C Treatment
Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2018 “Direct acting antivirals” cure over 99% in the course of the disease as a recent breakthrough treatment method in hepatitis C treatment. Possible drug-drug interactions should not be overlooked.
İrem Akdemir Kalkan +3 more
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Drugs and violence in Colombia: a VECM analysis [PDF]
, 2009 It has been widely argued that the production of illegal drugs, particularly cocaine, has financed guerrilla activity in Colombia. This paper uses quarterly time-series data for Colombia 1994-2005 to examine the interaction between legal agricultural ...
Gonzalez, T., Smith, Ron P.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source