Results 91 to 100 of about 5,892,906 (287)

DDIGIP: predicting drug-drug interactions based on Gaussian interaction profile kernels

open access: yesBMC Bioinformatics, 2019
Background A drug-drug interaction (DDI) is defined as a drug effect modified by another drug, which is very common in treating complex diseases such as cancer.
Cheng Yan   +4 more
doaj   +1 more source

Clustering drug-drug interaction networks with energy model layouts: community analysis and drug repurposing

open access: yesScientific Reports, 2016
Analyzing drug-drug interactions may unravel previously unknown drug action patterns, leading to the development of new drug discovery tools. We present a new approach to analyzing drug-drug interaction networks, based on clustering and topological ...
L. Udrescu   +6 more
semanticscholar   +1 more source

Pantoprazole – safety in drug-drug interaction

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by ...
E. V. Shikh, D. A. Sychev
doaj  

Drug-Drug Interaction Management in Hepatitis C Treatment

open access: yesAnkara Üniversitesi Tıp Fakültesi Mecmuas, 2018
“Direct acting antivirals” cure over 99% in the course of the disease as a recent breakthrough treatment method in hepatitis C treatment. Possible drug-drug interactions should not be overlooked.
İrem Akdemir Kalkan   +3 more
doaj   +1 more source

An Ontology for formal representation of Drug Drug Interaction Knowledge [PDF]

open access: yes, 2013
The poster at: The Sixth International Biocuration Conference (Biocuration 2013), took at April 7–10, 2013 in Churchill College, Cambridge, UK. The event web site in: http://www.ebi.ac.uk/biocuration2013/content/homeOntologies are useful tools in ...
Herrero Zazo, María   +2 more
core   +1 more source

Benchmarking network propagation methods for disease gene identification [PDF]

open access: yes, 2019
In-silico identification of potential target genes for disease is an essential aspect of drug target discovery. Recent studies suggest that successful targets can be found through by leveraging genetic, genomic and protein interaction information.
Barrett, Steven J.   +5 more
core   +2 more sources

Drug–drug interaction analysis: Antituberculosis drugs versus antiretroviral drugs

open access: yesBiomedical and Biotechnology Research Journal, 2019
Background: Human immunodeficiency virus (HIV) infection is an important public health globally. An important concomitant medical disorder among HIV-infected patients is tuberculosis. The management of concurrent infection between HIV and tuberculosis is
Won Sriwijitalai, Viroj Wiwanitkit
doaj   +1 more source

Kajian Interaksi Obat pada Pengobatan Pasien Gagal Ginjal Kronis Hipertensi di Rsup Sanglah Denpasar Tahun 2007 [PDF]

open access: yes, 2012
A research which observing drug interaction in chronic kidney diseasse hypertension compliance patients in RSUP Sanglah Denpasar has been carried out.
Prasetya, A. A. (A)   +2 more
core  

Mechanisms and the clinical relevance of complex drug–drug interactions

open access: yesClinical Pharmacology: Advances and Applications, 2018
Arthur G Roberts, Morgan E Gibbs Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, USA Abstract: As a result of an increasing aging population, the number of individuals taking multiple medications simultaneously has grown ...
Roberts AG, Gibbs ME
doaj  

LLM-Enhanced Multimodal Framework for Drug–Drug Interaction Prediction

open access: yesBiomedicines
Background: Drug–drug interactions (DDIs) involve pharmacokinetic or pharmacodynamic changes that occur when multiple drugs are co-administered, potentially leading to reduced efficacy or adverse effects.
Song Im, Younhee Ko
doaj   +1 more source

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