Results 41 to 50 of about 5,634,975 (396)

The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995–2010

BMC Medicine, 2015
BackgroundThe escalating use of prescribed drugs has increasingly raised concerns about polypharmacy. This study aims to examine changes in rates of polypharmacy and potentially serious drug-drug interactions in a stable geographical population between ...
B. Guthrie, B. Makubate, Virginia Hernández-Santiago, Tobias Dreischulte   +3 more
semanticscholar   +1 more source

Delta-9-Tetrahydrocannabinol and Cannabidiol Drug-Drug Interactions

Medical Cannabis and Cannabinoids, 2020
Although prescribing information (PI) is often the initial source of information when identifying potential drug-drug interactions, it may only provide a limited number of exemplars or only reference a class of medications without providing any specific ...
Paul T. Kocis, K. Vrana
semanticscholar   +1 more source

Choosing the safest acute combination therapy during prophylactic treatment. pharmacokinetic and pharmacodynamic considerations [PDF]

, 2015
Drugs used in the treatment of migraine have been recently reported to be highly associated with the occurrence of clinically significant drug-drug interactions (DDIs)
Lionetto, Luana, MARTELLETTI, Paolo
core   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Detecting drug-drug interactions using artificial neural networks and classic graph similarity measures [PDF]

PLoS ONE, 2019
Drug-drug interactions are preventable causes of medical injuries and often result in doctor and emergency room visits. Computational techniques can be used to predict potential drug-drug interactions.
Guy Shtar, L. Rokach, Bracha Shapira
semanticscholar   +1 more source

Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use

Journal of Clinical Medicine, 2019
Cannabidiol (CBD) is ubiquitous in state-based medical cannabis programs and consumer products for complementary health or recreational use. CBD has intrinsic pharmacologic effects and associated adverse drug events (ADEs) along with the potential for ...
Joshua D. Brown, A. Winterstein
semanticscholar   +1 more source

Drug-drug interactions with antiretroviral therapy among people living with HIV in Asia and other regions: Risk factors and impact on indicators of health-related quality of life

Population Medicine, 2022
Introduction While studies have extensively examined the clinical and pharmacokinetic correlates of drug-drug interactions (DDIs) with antiretroviral therapy (ART), less is known about DDIs from the perspective of people living with HIV (PLHIV). Among an
Sejun Park, Yu-Hsiang Hsiao, Fei Yu, Keita Kambara, Brent Allan, Garry Brough, Ta-Fen Hwang, Nathalie Dang, Benjamin Young, Rickesh Patel, Andres Maldonado, Chinyere Okoli   +11 more
doaj   +1 more source

Drug-drug interactions in the ICU [PDF]

Critical Care, 2009
The present study intended to identify and analyze the significance of drug–drug interaction (DDI) in critically ill patients.
S Ray, Subhash Todi, J Pramanik, M Bhattacharyya   +3 more
openaire   +2 more sources

Drug–Drug Interactions Involving Intestinal and Hepatic CYP1A Enzymes

Pharmaceutics, 2020
Cytochrome P450 (CYP) 1A enzymes are considerably expressed in the human intestine and liver and involved in the biotransformation of about 10% of marketed drugs.
Florian Klomp, Christoph Wenzel, M. Droździk, S. Oswald   +3 more
semanticscholar   +1 more source

A comprehensive evaluation of potentially significant drug-drug, drug-herb, and drug-food interactions among cancer patients receiving anticancer drugs

BMC Cancer, 2022
Introduction During the cancer treatment path, cancer patients use numerous drugs, including anticancer, supportive, and other prescribed medications, along with herbs and certain products.
Amer A. Koni, Maisa A. Nazzal, Bushra A. Suwan, Samah S. Sobuh, Najiya T. Abuhazeem, Asil N. Salman, Husam T. Salameh, Riad Amer, Sa’ed H. Zyoud   +8 more
doaj   +1 more source