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Drug-Induced Liver Disease

Critical Care Nursing Clinics of North America, 2010
More than 1000 drugs have been associated with hepatic injury, which can present in all forms of acute and chronic liver disease. The identification and prevention of drug-induced liver disease remain challenging tasks for health care professionals as reliable and practical assessment tools are not currently available to diagnose drug-induced liver ...
Jiwon W, Kim   +2 more
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Drug-induced liver disease

Current Opinion in Gastroenterology, 2001
This year's review is divided into several sections: the first describes drug withdrawals and new general reviews of drug-induced liver disease (DILD), including a review of a classification of drug injury. We review agents newly described as causing DILD, and new reports of DILD from established agents appearing in the year 2000. New aspects regarding
G, Marino, J H, Lewis
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Drug-induced liver disease

Current Opinion in Gastroenterology, 2006
To summarize the pertinent case reports, case series and clinical studies that described clinical, histological, epidemiological and mechanistic features of drug-induced liver disease in 2005.Acetaminophen, highly active antiretroviral therapy and drugs for tuberculosis retained their preeminent position as the most commonly reported agents causing ...
James H, Lewis   +3 more
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Drug-induced liver disease

Current Opinion in Gastroenterology, 1999
The past year has seen several additions to the list of drugs that cause hepatic injury. Many of these agents produce fulminant hepatic necrosis and, in some cases, were withdrawn from the market (eg, bromfenac). Other drugs had warnings placed in their labeling along with stringent monitoring guidelines to alert physicians and patients alike to the ...
W, Mayoral, J H, Lewis, H, Zimmerman
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Drug-induced Liver Disease

Medical Clinics of North America, 1989
The relative importance of drug-induced liver disease assumes much significance in certain groups of patients such as the elderly. The majority of cases occur as unexpected reactions to a therapeutic dose of a drug. Factors affecting susceptibility to drug-induced liver disease are diverse and are discussed in this article.
J H, Lewis, H J, Zimmerman
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Drug-Induced Liver Disease

Drugs, 1978
Drug-induced liver disease may account for between 10% and 50% of adult patients with elevated enzymes, especially in patients over age 50 years. It accounts for nearly 25% of patients with fulminant hepatic failure. Liver injury can be cytotoxic, cholestatic, or mixed.
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The Diagnosis of Drug-Induced Liver Disease

Current Clinical Pharmacology, 2006
The diagnosis of drug-induced liver injury is often one of exclusion with initial suspicion based on circumstantial evidence. The natural history, characteristics and limitations of this exclusion process are revised. Also, the numerous published attribution algorithms for evaluation of drug-related liver abnormalities are described and their ...
Pedro, Zapater   +2 more
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Drug-induced liver disease in 2003

Current Opinion in Gastroenterology, 2004
Drug-induced liver disease remains an important topic of concern for all prescribers as well as drug manufacturers. The withdrawal of troglitazone (Rezulin) and bromfenac (Duract) a few years ago remains fresh in the minds of regulatory authorities as well as clinicians and researchers who are focusing renewed attention on ways to better understand ...
Aline Charabaty, Pishvaian   +2 more
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Drug-induced liver disease in 2006

Current Opinion in Gastroenterology, 2007
To identify the key publications of 2006 dealing with drug-induced liver injury.When given in therapeutic doses over 14 days, acetaminophen produced significant asymptomatic elevations in alanine aminotransferase among healthy volunteers, suggesting that subclinical injury may be more common than previously thought.
Cherinne, Arundel, James H, Lewis
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Drug-Induced Liver Disease

Archives of Internal Medicine, 1965
DRUG-INDUCED hepatic injury, particularly that associated with jaundice, is becoming more frequent because of the increasing use of potent drugs. Nevertheless, its pathogenesis remains mysterious, and its classifications is difficult. Initially, drug-induced hepatic injury followed use of established hepatotoxins as exemplified by diethylene glycol ...
H, POPPER   +4 more
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