Results 91 to 100 of about 524,198 (385)

Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources [PDF]

, 2019
This is the peer reviewed version of the following article: Forns, J. [et al.]. Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources. "Pharmacoepidemiology and drug safety", 6 Juny 2019, vol.
Cainzos Achirica, Miguel, Castellsagué, Jordi, Cortés Martínez, Jordi, Deltour, Nicole, Forns, Joan, Giner Soriano, Maria, Hallas, Jesper, Hellfritzsch, M, Jacquot, Emmanuelle, Morros Padrós, Rosa, Pladevall, Miquel, Poblador Plou, Beatriz, Pottegard, Anton, Prados Torres, Alexandra, Pérez Gutthann, Susana   +14 more
core   +6 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Drug Induced Hepatotoxicity – An Ongoing Challenge

Journal of Bahria University Medical and Dental College, 2021
Drug induced liver injury is one of the main factor of liver failure and acute liver damage world wide with high incidence in western countries. Liver injury can be intrinsic (dose dependant) or idiosyncratic (dose independent).
Mehr Fatima, Syed Ijaz Hussain Zaidi
doaj   +1 more source

Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs

Chinese Medicine, 2021
Drug-induced liver injury (DILI) is a common adverse drug reaction (ADR) and a serious threat to health that affects disease treatments. At present, no targeted clinical drugs are available for DILI. Traditional natural medicines have been widely used as
Yongfeng Zhou, Junnan Wang, Dingkun Zhang, Jiaxin Liu, Qinghua Wu, Jiang Chen, Peng Tan, Boyu Xing, Yan-zhong Han, Ping Zhang, Xiaohe Xiao, J. Pei   +11 more
semanticscholar   +1 more source

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]

, 2019
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo, Esserman, Laura J, Hyland, Colby, Piawah, Sorbarikor, Rugo, Hope S, Umetsu, Sarah E   +5 more
core  

Combined activities of JNK1 and JNK2 in hepatocytes protect against toxic liver injury [PDF]

, 2015
Background & Aims: c-Jun N-terminal kinase (JNK)1 and JNK2 are expressed in hepatocytes and have overlapping and distinct functions. JNK proteins are activated, via phosphorylation, in response to acetaminophen- or CCl4-induced liver damage; the level of
Al Masaoudi, Malika, Bechmann, Lars P., Boekschoten, Mark V., Canbay, Ali E., Cubero, Francisco Javier, Davis, Roger J., Gassler, Nikolaus, Hu, Wei, Liedtke, Christian, Luedde, Tom, Muller, Michael, Nevzorova, Yulia A., Peng, Jin, Preisinger, Christian, Trautwein, Christian, Zhao, Gang, Zoubek, Miguel Eugenio   +16 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Case of Ibuprofen-Induced Liver Injury

Annals of Internal Medicine: Clinical Cases, 2023
Drug-induced liver injury (DILI) resulting from nonsteroidal anti-inflammatory drugs (NSAIDs) is a rare phenomenon; however, several cases have been reported in the literature and the LiverTox database.
Kirsten Wong, Beda Cha, Simon Wu
doaj   +1 more source

Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

Scientific Reports, 2021
Drug-induced liver injury (DILI) causes one in three market withdrawals due to adverse drug reactions, causing preventable human suffering and massive financial loss.
H. Dirven, G. Vist, S. Bandhakavi, J. Mehta, S. Fitch, P. Pound, R. Ram, Breanne Kincaid, C. Leenaars, Minjun Chen, Robert A. Wright, K. Tsaioun   +11 more
semanticscholar   +1 more source

Concentración, segregación y movilidad residencial de los extranjeros en Barcelona [PDF]

, 2011
El artículo analiza la dinámica residencial de la población extranjera en la ciudad de Barcelona, considerando tres aspectos que centran su distribución: la concentración en el territorio, la segregación residencial en relación con la población de la ...
Aithal, Guruprasad P., Barnhart, Huiman X., Chalasani, Naga, Cirulli, Elizabeth Theresa, Daly, Ann K., Dillon, John F., Drug-Induced Liver Injury Network (DILN), Fontana, Robert John, International Serious Adverse Events Consortium (iSAEC), Long, Nanye, Navarro, Victor, Nicoletti, Paola, Odin, Joseph, Ostrov, David, Pharmacogenetics of Drug-Induced Liver Injury Group (DILIGEN), Serrano, Jose, Stolz, Andrew, Urban, Thomas Jacob, Watkins, Paul Brent   +18 more
core   +9 more sources