Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
[Research progress in the field of drug-induced liver injury in 2025]. [PDF]
Zhi Y, Dong YN, Lei XH, Mao YM.
europepmc +1 more source
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang +10 more
wiley +1 more source
Idiosyncratic Drug-Induced Liver Injury and Trastuzumab Deruxtecan in Breast Cancer: A Case Report. [PDF]
Lisanti C +9 more
europepmc +1 more source
Azathioprine-Induced Eosinophilia and Acute Cholestatic Hepatitis in Lupus Nephritis: An Early Hypersensitivity-Mediated Presentation of Thiopurine-Associated Drug-Induced Liver Injury. [PDF]
Ali S +5 more
europepmc +1 more source
Drug-Induced Liver Injury Associated With Turmeric and Black Pepper Based Dietary Supplements Consumption: A Case Report. [PDF]
Pugnale S, Schilter L, Galofaro L.
europepmc +1 more source
[Gut microbiota-associated metabolites with drug-induced liver injury]. [PDF]
Gao WK +5 more
europepmc +1 more source
Drug-Induced Liver Injury Secondary to Turmeric Supplement Containing Piperine: A Case Report. [PDF]
Koo N, Kambhampati H, Herman M.
europepmc +1 more source
A Case Report: Drug-Induced Liver Injury from Prolonged Topical Application of Noni (<i>Morinda citrifolia</i>). [PDF]
Kim CJ +6 more
europepmc +1 more source
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In the usual course of events, the liver detoxifies hepatocytotoxic intermediates of drug metabolism. But when protective systems are overloaded by normally harmless drugs, the intermediates can cause massive, even fatal, hepatic necrosis.
J R, Mitchell, B H, Lauterburg
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