Results 41 to 50 of about 402,646 (342)
A dog model for acetaminophen-induced fulminant hepatic failure. [PDF]
, 1989 The development of a large animal model of fulminant hepatic failure produced with acetaminophen that should be useful in the development and evaluation of potential medical therapies for the important clinical problem of fulminant hepatic failure is ...
Barone, M +7 more
core +1 more source
Impact of Non-Alcoholic Simple Fatty Liver Disease on Antituberculosis Drug-Induced Liver Injury
Infection and Drug Resistance, 2021 Yi-Hui Liu,1 Yan Guo,2 Hong Xu,1 Hui Feng,1 Dong-Ya Chen1 1Department of Digestive Hepatology, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, 310003, People’s Republic of China; 2Department of Gastroenterology, Hangzhou Third Hospital, Hangzhou ...
Liu YH, Guo Y, Xu H, Feng H, Chen DY
doaj
Drug induced liver injury: do we still need a routine liver biopsy for diagnosis today?
Annals of Hepatology, 2014 For the pathologist, the diagnosis of drug induced liver injury (DILI) is challenging, because histopathological features mimic all primary hepatic and biliary diseases, lacking changes that are specific for DILI.
Rolf Teschke, Christian Frenzel
doaj +1 more source
BMC Pediatrics, 2021 Background Drug-induced aseptic meningitis is a rare, but challenging diagnosis, most commonly reported with nonsteoroidal anti-inflammatory drugs (NSAIDs) and antibiotics.
J. A. A. van Asperdt, R. A. De Moor
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Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review
Molecules, 2023 The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to damage from various factors such as viral infections, drug reactions, excessive alcohol consumption, and autoimmune diseases.
Xiaoyangzi Li +6 more
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Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity
ToxinsColchicine, a natural compound extracted from Colchicum autumnale, is a phytotoxin, but interestingly, it also has multiple pharmacological activities.
Ruoyue Huang +5 more
doaj +1 more source
Репродуктивная эндокринология, 2018 Liver is the main organ that plays an important role in the biotransformation of medicine in human body. Therefore, drug-induced liver injuries are much more common than official medical statistics show in different countries and on different continents.
А. А. Суханова +2 more
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Evaluation of drug-induced liver injury as etiology for acute liver failure in Brazil
Annals of Hepatology, 2021 Introduction and objectives: Little is known about the etiology of acute liver failure (ALF) in Latin America. The objective of this paper is to investigate the main etiologies of ALF in Brazil, including Drug Induced Liver Injury (DILI) using stringent ...
Genario Santos +15 more
doaj +1 more source
Hepatitis E Virus Detection in Liver Tissue from Patients with Suspected Drug-Induced Liver Injury [PDF]
, 2015 Hepatitis E virus (HEV) infection is increasingly recognized as a cause of acute hepatitis in the industrialized world. We aimed to determine the frequency of acute Hepatitis E virus (HEV) infection in cases of suspected drug-induced liver injury (DILI),
Achim Weber +3 more
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source