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Drug-Induced Liver Injury

Archives of Pathology & Laboratory Medicine, 2015
Context Drug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufactured or naturally occurring chemical compound. Drug-induced liver injury is of major concern owing to the ever increasing number of compounds introduced into the market for treatment of various ...
Kurt, Fisher, Raj, Vuppalanchi, Romil, Saxena   +2 more
openaire   +2 more sources

Mechanisms of drug-induced liver injury [PDF]

The AAPS Journal, 2006
The idiosyncratic nature and poor prognosis of drug-induced liver injury (DILI) make this type of reaction a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The key to predicting and preventing DILI is understanding the underlying mechanisms.
Michael P, Holt, Cynthia, Ju
openaire   +2 more sources

Tuberculosis Drug-Induced Liver Injury

Jurnal Respirasi, 2020
Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO).
Soedarsono Soedarsono, Agustinus Rizki Wirawan Riadi   +1 more
doaj   +1 more source

MicroRNAs in Drug-induced Liver Injury [PDF]

Journal of Clinical and Translational Hepatology, 2014
Drug-induced liver injury (DILI) is a leading cause of acute liver failure, and a major reason for the recall of marketed drugs. Detection of potential liver injury is a challenge for clinical management and preclinical drug safety studies, as well as a great obstacle to the development of new, effective and safe drugs.
Li, Li-Min, Wang, Dong, Zen, Ke
openaire   +2 more sources

Drug-Induced Liver Injuries (Clinical Guidelines for Physicians)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2019
Aim. Clinical guidelines for the management of adult patients suffering from drug-induced liver injuries (DILI) are intended for all medical specialists, who treat such patients in their clinical practice.Key findings.
Vladimir T. Ivashkin, Andrey Yu. Baranovsky, Karina L. Raikhelson, Lyudmila K. Palgova, Marina V. Maevskaya, Elina A. Kondrashina, Natalya V. Marchenko, Tatyana P. Nekrasova, Igor G. Nikitin   +8 more
doaj   +1 more source

Case series and review of Ayurvedic medication induced liver injury

BMC Complementary Medicine and Therapies, 2021
Background Complementary and alternative medicine use among Americans is prevalent. Originating in India, Ayurvedic medicine use in the United States has grown 57% since 2002.
Christopher M. Karousatos, Justin K. Lee, David R. Braxton, Tse-Ling Fong   +3 more
doaj   +1 more source

Epidemiology of drug-induced liver injury in a University Hospital from Colombia: Updated RUCAM being used for prospective causality assessment

Annals of Hepatology, 2019
Introduction and aim: Epidemiological information regarding drug-induced liver injury in some Latin American countries remains limited. Therefore, disease prevention and health promotion strategies are imperative to reduce drug-induced liver injuries and
Alejandra Cano-Paniagua, Pedro Amariles, Nancy Angulo, Margarita Restrepo-Garay   +3 more
doaj   +1 more source

Rational choice of hepatoprotectors for drug-induced liver injury

Gastroenterologìa, 2022
The article deals with a review of the current literature on the clinical use of hepatoprotectors in drug-induced liver injury. The literature was searched in Scopus, Web of Science, PubMed and other databases. Risk factors, pathogenetic mechanisms of li­
H.V. Osyodlo, M.P. Boichak, O.O. Fedorova   +2 more
doaj   +1 more source

Dietary Intake of Vegetables and Cooking Oil Was Associated With Drug-Induced Liver Injury During Tuberculosis Treatment: A Preliminary Cohort Study

Frontiers in Nutrition, 2021
Background and Purpose: Drug-induced liver injury is challenging during tuberculosis treatment. There is no epidemiological data investigating the relation between dietary intake and the risk of drug-induced liver injury during tuberculosis treatment ...
Jinyu Wang, Ke Xiong, Lei Xu, Chao Zhang, Shanliang Zhao, Yufeng Liu, Aiguo Ma   +6 more
doaj   +1 more source

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

Bengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy, Muniruddin SK, Subham Mondal, Sandipan Mukherjee, Santa Subhra Chatterjee   +4 more
doaj   +1 more source