Results 11 to 20 of about 245,919 (260)
Ivermectin drug induced liver injury
South African Medical Journal, 2023 Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.
Mark Sonderup +2 more
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Treatment of Drug-Induced Liver Injury
Biomedicines, 2022 Current pharmacotherapy options of drug-induced liver injury (DILI) remain under discussion and are now evaluated in this analysis. Needless to say, the use of the offending drug must be stopped as soon as DILI is suspected.
Rolf Teschke
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Drug-induced liver injury [PDF]
Canadian Medical Association Journal, 2021 Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Kumachev, Alexander, Wu, Peter E.
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Drug-Induced Liver Injury [PDF]
AACN Advanced Critical Care, 2016 Drug-induced liver injury (DILI) can result from both idiosyncratic and intrinsic mechanisms. This article discusses the clinical impact of DILI from a broad range of medications as well as herbal and dietary supplements. Risk factors for idiosyncratic DILI (IDILI) are the result of multiple host, environmental, and compound factors.
Leslie A, Hamilton +2 more
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Critical Care Nursing Clinics of North America, 2022 Drug-induced liver injury (DILI) is a spectrum of liver injuries that can be classified by phenotype and injury patterns. Some injury patterns can be predicted in a number of drugs that are commonly used in practice, but idiosyncratic reactions are unpredictable and are not dose related.
Narendra Singh Choudhary +4 more
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Drug-Induced Liver Injury [PDF]
Mayo Clinic Proceedings, 2014 Drug hepatoxicity can be nonidiosyncratic (predictable), as in the case of acetaminophen, or idiosyncratic (unpredictable). This review article focuses primarily on idiosyncratic drug-induced liver injury (DILI). New epidemiologic data suggest that approximately 20 new cases of DILI per 100,000 persons occur each year.
Michael D, Leise +2 more
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Pharmacogenetics of drug‐induced liver injury† [PDF]
Hepatology, 2010 Recent progress in research on drug-induced liver injury (DILI) has been determined by key developments in two areas. First, new technologies allow the identification of genetic risk factors with improved sensitivity, specificity, and efficiency.
Russmann Stefan +2 more
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Mechanisms of drug-induced liver injury [PDF]
The AAPS Journal, 2006 The idiosyncratic nature and poor prognosis of drug-induced liver injury (DILI) make this type of reaction a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The key to predicting and preventing DILI is understanding the underlying mechanisms.
Michael P, Holt, Cynthia, Ju
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Archives of Pathology & Laboratory Medicine, 2015 Context Drug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufactured or naturally occurring chemical compound. Drug-induced liver injury is of major concern owing to the ever increasing number of compounds introduced into the market for treatment of various ...
Kurt, Fisher +2 more
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Tuberculosis Drug-Induced Liver Injury
Jurnal Respirasi, 2020 Effective tuberculosis (TB) treatment requires a combination of bactericidal and/or bacteriostatic TB drugs. The combination of these regimens is the standard therapy recommended by World Health Organization (WHO).
Soedarsono Soedarsono +1 more
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