Results 91 to 100 of about 964 (152)

The role of endoplasmic reticulum aminopeptidase ERAP2 pathogenic mutation rs1363907 in amoxicillin clavulanate-induced liver injury: a special case report

Frontiers in Pharmacology
Idiosyncratic hepatotoxicity is a type of drug-induced liver injury (DILI) that is unpredictable and clinically severe, and amoxicillin clavulanate (AC) is the most implicated drug in DILI worldwide. The clinical manifestations of amoxicillin clavulanate-
Yan Zhan, Yan Zhan, Yan Zhan, Yan Zhan, Jin-Mao Liao, Ling Ye, Ling Ye, Ling Ye, Ling Ye, Long Zhang, Long Zhang, Long Zhang, Long Zhang, Long Zhang, Zheng Zhang, Ji-Ye Yin, Ji-Ye Yin, Ji-Ye Yin, Ji-Ye Yin   +18 more
doaj   +1 more source

Drug induced liver injury: accuracy of diagnosis in published reports

Annals of Hepatology, 2014
The diagnosis of drug induced liver injury (DILI) is based primarily on the exclusion of alternative causes. To assess the frequency of alternative causes in initially suspected DILI cases, we searched the Medline database with the following terms: drug ...
Rolf Teschke, Christian Frenzel, Albrecht Wolff, Axel Eickhoff, Johannes Schulze   +4 more
doaj  

Drug-induced liver injury. Part I: Classification, diagnosis and treatment

Clinical & Experimental Hepatology
Drug-induced liver injury (DILI) is a growing clinical problem. Antibiotics remain the most common cause of DILI in Europe. Their clinical spectrum is very broad, from asymptomatic to acute liver failure. Currently, DILI is categorized as hepatocellular (
Dorota M. Kozielewicz, Piotr Stalke, Julita Skrzypek   +2 more
doaj   +1 more source

A brief overview of drug-induced liver damage

The Egyptian Journal of Internal Medicine
Drug-induced liver injury (DILI) is a prevalent disorder that can be led on by almost all drug types. The majority of benign DILI cases become better after drug discontinuation.
Soumyadip Roy, Zalak Shah, G. S. Chakraborthy   +2 more
doaj   +1 more source

S3111 An Unusual Case of Acute Liver Failure Secondary to Autoimmune Hepatitis (AIH) From Drug-Induced Liver Injury (DILI)

, 2022
Abid Ahmad, Howard C. Masuoka, John Guardiola   +2 more
openalex   +1 more source

Progress in the treatment of drug-induced liver injury with natural products

Pharmacological Research, 2022
There are numerous prescription drugs and non-prescription drugs that cause drug-induced liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its mechanism becomes clearer as the disease is studied further.
Yuan-kai Sun, Ya-fei Zhang, Li Xie, Fan Rong, Xing-yu Zhu, Jing Xie, Huan Zhou, Tao Xu   +7 more
doaj  

Drug-Induced Liver Injury (DILI) related to Propylthiouracil (PTU) in hyperthyroidism with liver cirrhosis

, 2023
Arina Salsabila, Ulfa Kholili, Hermina Novida   +2 more
openalex   +2 more sources

EGCG inhibits ferroptosis to ameliorate APAP-induced liver injury by suppressing NEDD8 and stabilizing HUWE1 in vivo and in vitro

Acta Materia Medica
Excessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote.
Zijun Ouyang, Tao Zhang, Mengting Liu, Fufu Li, Hui Guo, Yanhui Li, Jieyu Chen, Feiyang Wang, Yang Sun, Dong Liu, Haiyan Sun   +10 more
doaj   +1 more source

Puromycin selection of cells with a high expression of the cytochrome P450 CYP3A4 gene activity from a patient with drug-induced liver injury (DILI) and their lifespan prolongation using a combination of CDK4^R24C, cyclin D1 and TERT

, 2020
Shoko Miyata, Noriaki Saku, Palaksha Kanive Javaregowda, Kenta Ite, Masashi Toyoda, Tōru Kimura, Hiroshi Nishina, Atsuko Nakazawa, Mureo Kasahara, Hidenori Nonaka, Tohru Kiyono, Akihiro Umezawa   +11 more
openalex   +1 more source

Exploring drug-induced liver injury: comprehensive insights into mechanisms and management of hepatotoxic agents

Future Journal of Pharmaceutical Sciences
Background Drug-induced liver injury (DILI) is a significant adverse drug reaction, manifesting through a range of clinical presentations from mild liver enzyme to acute liver failure.
Ahmed K. Saleh, Thanaa A. El-Masry, Aya H. El-Kadem, Nada A. Ashour, Nageh A. El-Mahdy   +4 more
doaj   +1 more source