Results 171 to 180 of about 26,575 (260)
Albendazole-induced granulomatous hepatitis: a case report [PDF]
, 2013 INTRODUCTION: Drug-related hepatotoxicity is a common medical problem with implications for health systems. It constitutes a cause of acute liver failure and, in many cases, is responsible for the rejection of new pharmacological agents during efficacy ...
Andres Eduardo Marin Castro +3 more
core +1 more source
Drug-induced liver injury. Part I: Classification, diagnosis and treatment
Clinical & Experimental HepatologyDrug-induced liver injury (DILI) is a growing clinical problem. Antibiotics remain the most common cause of DILI in Europe. Their clinical spectrum is very broad, from asymptomatic to acute liver failure. Currently, DILI is categorized as hepatocellular (
Dorota M. Kozielewicz +2 more
doaj +1 more source
Identification of the additional mitochondrial liabilities of 2-hydroxyflutamide when compared to its parent compound, flutamide in HepG2 cells [PDF]
, 2016 The androgen receptor antagonist, flutamide, is strongly associated with idiosyncratic drug-induced liver injury (DILI). Following administration, flutamide undergoes extensive first-pass metabolism to its primary metabolite, 2-hydroxyflutamide ...
Alfirevic, A +4 more
core +1 more source
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
, 2011 Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen +3 more
core +1 more source
Pharmacokinetic and Pharmacogenetic aspects of drug-drug interactions between antiretroviral and anti-tuberculosis drugs in Ethiopian patients: Implication for optimization of TB-HIV co-treatment [PDF]
, 2013 TB and HIV are immuno-pathologically interacting epidemic infectious diseases affecting the lives of millions globally & sub-Saharan African region accounts the highest burden of both diseases.
Habtewolde Eyakem, Abiy
core +1 more source
Gastro Hep AdvancesDrug-induced liver injury (DILI) is a rare but serious complication of Helicobacter pylori eradication therapy, especially in patients with pre-existing liver disease. We report a 75-year-old man with well-controlled primary biliary cholangitis (PBC) who
Taro Nakajima +6 more
doaj +1 more source
A brief overview of drug-induced liver damage
The Egyptian Journal of Internal MedicineDrug-induced liver injury (DILI) is a prevalent disorder that can be led on by almost all drug types. The majority of benign DILI cases become better after drug discontinuation.
Soumyadip Roy +2 more
doaj +1 more source
Acta Materia MedicaExcessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote.
Zijun Ouyang +10 more
doaj +1 more source