Results 51 to 60 of about 12,091 (224)

Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources [PDF]

, 2019
This is the peer reviewed version of the following article: Forns, J. [et al.]. Validity of ICD-9 and ICD-10 codes used to identify acute liver injury: a study in three European data sources. "Pharmacoepidemiology and drug safety", 6 Juny 2019, vol.
Cainzos Achirica, Miguel, Castellsagué, Jordi, Cortés Martínez, Jordi, Deltour, Nicole, Forns, Joan, Giner Soriano, Maria, Hallas, Jesper, Hellfritzsch, M, Jacquot, Emmanuelle, Morros Padrós, Rosa, Pladevall, Miquel, Poblador Plou, Beatriz, Pottegard, Anton, Prados Torres, Alexandra, Pérez Gutthann, Susana   +14 more
core   +6 more sources

The Immunological Mechanisms and Immune-Based Biomarkers of Drug-Induced Liver Injury

Frontiers in Pharmacology, 2021
Drug-induced liver injury (DILI) has become one of the major challenges of drug safety all over the word. So far, about 1,100 commonly used drugs including the medications used regularly, herbal and/or dietary supplements, have been reported to induce ...
Wenhui Liu, Wenhui Liu, Wenhui Liu, Wenhui Liu, Xiangchang Zeng, Xiangchang Zeng, Xiangchang Zeng, Xiangchang Zeng, Yating Liu, Yating Liu, Yating Liu, Yating Liu, Jinfeng Liu, Jinfeng Liu, Jinfeng Liu, Jinfeng Liu, Chaopeng Li, Lulu Chen, Hongying Chen, Hongying Chen, Hongying Chen, Hongying Chen, Dongsheng Ouyang, Dongsheng Ouyang, Dongsheng Ouyang, Dongsheng Ouyang, Dongsheng Ouyang   +26 more
doaj   +1 more source

Liver safety assessment: required data elements and best practices for data collection and standardization in clinical trials. [PDF]

, 2014
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access.A workshop was convened to discuss best practices
Andrade, Raul J, Avigan, Mark I, Bjornsson, Einar S, Cooper, Charles, Lewis, James H, Merz, Michael, Pasanen, Markku, Watkins, Paul B   +7 more
core   +2 more sources

A gene expression profile-based approach to screen the occurrence and predisposed host characteristics of drug-induced liver injury: a case study of Psoralea corylifolia Linn

Frontiers in Chemistry, 2023
Drug-induced liver injury (DILI) is one of the most common causes of a drug being withdrawn, and identifying the culprit drugs and the host factors at risk of causing DILI has become a current challenge. Recent studies have found that immune status plays
Ming-Liang Zhang, Ming-Liang Zhang, Ming-Liang Zhang, Ming-Liang Zhang, Wei-Xia Li, Wei-Xia Li, Wei-Xia Li, Wei-Xia Li, Xiao-Yan Wang, Xiao-Yan Wang, Xiao-Yan Wang, Xiao-Yan Wang, Hui Zhang, Hui Zhang, Hui Zhang, Hui Zhang, Ya-Li Wu, Ya-Li Wu, Ya-Li Wu, Ya-Li Wu, Liu-Qing Yang, Liu-Qing Yang, Liu-Qing Yang, Liu-Qing Yang, Xiao-Fei Chen, Xiao-Fei Chen, Xiao-Fei Chen, Xiao-Fei Chen, Shu-Qi Zhang, Shu-Qi Zhang, Shu-Qi Zhang, Shu-Qi Zhang, Yu-Long Chen, Ke-Ran Feng, Ke-Ran Feng, Ke-Ran Feng, Ke-Ran Feng, Jin-Fa Tang, Jin-Fa Tang, Jin-Fa Tang, Jin-Fa Tang, Jin-Fa Tang   +41 more
doaj   +1 more source

Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury [PDF]

, 2017
BACKGROUND & AIMS: Drug-induced liver injury (DILI) has features similar to those of other liver diseases including autoimmune hepatitis (AIH). We aimed to characterize the clinical and autoimmune features of liver injury caused by nitrofurantoin ...
Chalasani, Naga, de Boer, Ynto S., Drug-Induced Liver Injury Network., Hoofnagle, Jay H., Kleiner, David E., Kosinski, Andrzej S., Long, Nanye, Urban, Thomas J., Zhao, Zhen   +8 more
core   +2 more sources

A Complex Case of Cholestasis in a Patient with ABCB4 and ABCB11 Mutations [PDF]

, 2018
The low-phospholipid-associated cholelithiasis (LPAC) syndrome is a form of symptomatic cholelithiasis occurring in young adults, characterized by recurrence of symptoms after cholecystectomy and presence of hepatolithiasis.
Anapaz, V, Branco, J, Cardoso, M, Carvalho, R, Horta, D, Martins, A, Reis, J, Rodrigues, C   +7 more
core   +1 more source

Bacteroides fragilis 839 ameliorates anti-tuberculosis drugs-induced liver injury by suppressing inflammation and regulating gut microbiota in mice

Frontiers in Medicine
Anti-tuberculosis drug-induced liver injury (ATB-DILI), caused by first-line anti-tuberculosis (anti-TB) drugs, disrupts treatment and increases the risk of drug resistance.
Qiujuan Li, Chenbing Wu, Kangshuai Zhang, Ziyi Zhou, Jing Li, Jie Bai, Jun Cao, Xiaoxia Shi   +7 more
doaj   +1 more source

Chronic Drug-Induced Liver Injury: Updates and Future Challenges

Frontiers in Pharmacology, 2021
Chronic drug-induced liver injury (DILI), defined as DILI with persistent liver injury more than one year after the first onset by the latest European guidelines, is a notable challenge globally with big issues of defining causality and establishing ...
Qiaoling Wang, Qiaoling Wang, Ang Huang, Jia-Bo Wang, Jia-Bo Wang, Zhengsheng Zou, Zhengsheng Zou   +6 more
doaj   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Drug-induced liver injury [PDF]

, 2010
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open)Drug-induced liver injury (DILI) is a well known adverse reaction of many drugs. Direct toxic liver damage is associated with paracetamol toxicity
Einar S. Björnsson
core