Results 251 to 260 of about 74,202 (303)

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

Epilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie, Inge M. W. Verberk, Jans S. van Ool, Anneke J. J. Rampen, Rebecca Z. Rousset, Nicole I. Wolf, Dederieke A. M. Maes‐Festen, Clara D. M. van Karnebeek, Charlotte E. Teunissen, Erik Boot, Agnies M. van Eeghen   +10 more
wiley   +1 more source

Restoration of Normal Brain Connectivity With Deep Brain Stimulation for Drug-Resistant Epilepsy in a Pediatric Patient. [PDF]

Cureus
Martin Del Campo I, Sandoval-Bonilla BA.
europepmc   +1 more source

Redefining drug-resistant epilepsy: Insights from an Italian Delphi consensus study. [PDF]

Epilepsia Open
Vigevano F, Bagnasco I, Di Gennaro G, Mecarelli O, Lattanzi S.   +4 more
europepmc   +1 more source

Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy. [PDF]

Clin Proteomics
Kangas P, Nyman TA, Metsähonkala L, Junnila J, Karttunen J, Jokinen TS.   +5 more
europepmc   +1 more source

Health economic analysis of seizure-related emergency visits of pediatric patients with drug-resistant epilepsy in Japan. [PDF]

Epilepsy Behav Rep
Fujimoto A, Kumagai T, Yamamoto K, Iwasaki K, Kokubo K, Igarashi A.   +5 more
europepmc   +1 more source

Disease duration modulates BOLD representations of alpha oscillations in drug-resistant epilepsy: A concurrent EEG and fMRI study. [PDF]

Epilepsia
Sie JH, Lee HJ, Shih YC, Chou CC, Chen C, Niddam D, Yu HY, Lin FH, Kuo WJ.   +8 more
europepmc   +1 more source

Corrigendum to "The use of cannabidiol as adjunctive therapy in adult patients with drug-resistant epilepsy: a systematic review and meta-analysis". [PDF]

Ther Adv Neurol Disord
europepmc   +1 more source

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Drug-Resistant Epilepsy

New England Journal of Medicine, 2011
Nearly a quarter of patients with seizures have drug-resistant epilepsy. This review examines how this diagnosis should be established and how to recognize pseudoresistance. It explains possible mechanisms of drug-resistant epilepsy and presents treatment strategies.
Katsuhiro, Kobayashi, Harumi, Yoshinaga, Yoko, Ohtsuka   +2 more
exaly   +10 more sources

Resective Epilepsy Surgery for Drug-Resistant Focal Epilepsy

JAMA, 2015
Epilepsy surgery is indicated for patients with focal seizures who do not respond to appropriate antiepileptic drug therapy consisting of 2 or more medications.To review resective surgery outcomes for focal epilepsy, to identify which patients benefit the most, and to discuss why epilepsy surgery may not be universally accepted.Medline and Cochrane ...
Barbara C, Jobst, Gregory D, Cascino
openaire   +4 more sources

Drug resistance in epilepsy

The Lancet Neurology, 2023
Drug resistance is estimated to affect about a third of individuals with epilepsy, but its prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other factors such as age of seizure onset and presence of associated neurological deficits.
Emilio Perucca, Piero Perucca, H Steve White, Elaine C Wirrell   +3 more
openaire   +2 more sources