Results 71 to 80 of about 86,450 (250)

The challenge of drug-resistant tuberculosis

Cleveland Clinic Journal of Medicine, 1994
CLINICAL ISSUES: After declining for decades, the incidence of tuberculosis is again increasing, and strains resistant to multiple drugs are appearing. The greatest increases in infection have been in blacks and Hispanics. The disease is most aggressive in patients infected with human immunodeficiency virus and in patients receiving immunosuppressive ...
openaire   +2 more sources

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Investigation of the cell composition and gene expression in the delayed-type hypersensitivity tuberculin skin test

Military Medical Research, 2023
Hui-Juan Duan, Hong-Qian Chu, Ting-Ming Cao, Guang-Ming Dai, Na Tian, Gang Sheng, Zhao-Gang Sun   +6 more
doaj   +1 more source

Identification of important modules and biomarkers in tuberculosis based on WGCNA

Frontiers in Microbiology
BackgroundTuberculosis (TB) is a significant public health concern, particularly in China. Long noncoding RNAs (lncRNAs) can provide abundant pathological information regarding etiology and could include candidate biomarkers for diagnosis of TB. However,
Jing Dong, Jing Dong, Jing Dong, Ruixue Song, Ruixue Song, Ruixue Song, Xuetian Shang, Xuetian Shang, Xuetian Shang, Yingchao Wang, Yingchao Wang, Yingchao Wang, Qiuyue Liu, Qiuyue Liu, Zhiguo Zhang, Hongyan Jia, Hongyan Jia, Hongyan Jia, Mailing Huang, Mailing Huang, Chuanzhi Zhu, Chuanzhi Zhu, Chuanzhi Zhu, Qi Sun, Qi Sun, Qi Sun, Boping Du, Boping Du, Boping Du, Aiying Xing, Aiying Xing, Aiying Xing, Zihui Li, Zihui Li, Zihui Li, Lanyue Zhang, Lanyue Zhang, Lanyue Zhang, Liping Pan, Liping Pan, Liping Pan, Zongde Zhang, Zongde Zhang, Zongde Zhang   +43 more
doaj   +1 more source

DRUG RESISTANT TUBERCULOSIS [PDF]

Medical Journal Armed Forces India, 1997
S P, Kalra, S C, Tewari, R, Jayaswal
openaire   +2 more sources

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Successful treatment of pre-extensively drug-resistant tuberculous meningoencephalomyelitis in pregnancy with a bedaquiline and delamanid-based regimen: a case report

BMC Infectious Diseases
Background Management of pre-extensively drug-resistant tuberculosis (pre-XDR-TB) during pregnancy poses a formidable clinical challenge, particularly when complicated by tuberculous meningoencephalomyelitis (TBMEM), While the WHO operational handbook ...
Qi Nie, Yuan Liu, Fan Xiao, Yong Zhou, Tingting Fu, Lijuan Zheng, Dongmei Huang, Qiuping Tang, Ting Liu, Lixuan Tao   +9 more
doaj   +1 more source

The study on the association between Beijing genotype family and drug susceptibility phenotypes of Mycobacterium tuberculosis in Beijing

Scientific Reports, 2017
The predominant prevalent Mycobacterium tuberculosis (M. tb) lineage was the Beijing genotype family in Beijing. There has been no systematic study on the association between drug resistance and Beijing genotype. Here we collected 268 M.
Yi Liu, Xiaoying Jiang, Wensheng Li, Xuxia Zhang, Wei Wang, Chuanyou Li   +5 more
doaj   +1 more source

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

Clinical Pharmacology &Therapeutics, EarlyView.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell, Antonio Lombardi, William Brumskine, Lali Mikiashvili, Kim Boekelheide, Joanna Moreira, Alda Holsta, Matthew Betteridge, Lindsay Thompson, Angela Crook, Paul Bruinenberg, Maria Beumont, Eugene Sun, Francesca Conradie   +13 more
wiley   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source