Results 61 to 70 of about 2,897,181 (203)

Drug-resistant tuberculosis in the 1990s [PDF]

open access: yesEuropean Respiratory Journal, 1995
There has been an upsurge of tuberculosis in many parts of the world in the past decade. The high rates of drug-resistant tuberculosis currently reported in many countries are alarming. The most catastrophic phenomenon is the emergence of multidrug-resistant strains of Mycobacterium tuberculosis.
W W, Yew, C H, Chau
openaire   +2 more sources

Case report: A 9-year systematic treatment failure of a pulmonary tuberculosis patient

open access: yesFrontiers in Public Health, 2022
ObjectiveTo explore the reasons of failure in a case of pulmonary tuberculosis (PTB) after 9 years systematic treatment.MethodsWe extracted the patients' treatment history, drug susceptibility testing (DST), Computed tomography (CT) images, and sequenced
Hui Jiang   +30 more
doaj   +1 more source

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

open access: yes, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
Ticona, E.   +64 more
core   +2 more sources

Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus

open access: yesMicrobiology Spectrum
Given the intrinsic resistance of Mycobacterium abscessus to a wide range of conventional antibiotics, it is urgent to explore new therapeutic approaches to manage this infection effectively. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), a proton pump
Jifang Zheng   +6 more
doaj   +1 more source

Analysis on Drug-Resistance-Associated Mutations among Multidrug-Resistant Mycobacterium tuberculosis Isolates in China

open access: yesAntibiotics, 2021
As the causative bacteria of tuberculosis, Mycobacteriumtuberculosis (M. tb) is aggravated by the emergence of its multidrug-resistant isolates in China.
Hongbing Jia, Yuhui Xu, Zhaogang Sun
doaj   +1 more source

Identification of 2-Aminothiazole-4-Carboxylate derivatives active against mycobacterium tuberculosis H37Rv and the beta-ketoacyl-ACP synthase mtFabH [PDF]

open access: yes, 2009
Tuberculosis (TB) is a disease which kills two million people every year and infects approximately over one-third of the world's population. The difficulty in managing tuberculosis is the prolonged treatment duration, the emergence of drug resistance and
Al-Jaidi, Bilal   +12 more
core   +4 more sources

Evaluation of a PCR-based universal heteroduplex generator assay as a tool for rapid detection of multidrug-resistant Mycobacterium tuberculosis in Peru.

open access: yes, 2003
Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and ...
Sonia H. Montenegro   +22 more
core   +1 more source

Treatment of Drug-Resistant Tuberculosis [PDF]

open access: yesClinics in Chest Medicine, 2019
The treatment of drug-resistant tuberculosis (TB) is complicated and has evolved significantly in the past decade with the advent of rapid molecular tests and updated evidence-based guidelines of the World Health Organization and other organizations.
Sundari R, Mase, Terence, Chorba
openaire   +2 more sources

Label-Free Quantitative Proteomics Identifies Novel Plasma Biomarkers for Distinguishing Pulmonary Tuberculosis and Latent Infection

open access: yesFrontiers in Microbiology, 2018
The lack of effective differential diagnostic methods for active tuberculosis (TB) and latent infection (LTBI) is still an obstacle for TB control. Furthermore, the molecular mechanism behind the progression from LTBI to active TB has been not elucidated.
Huishan Sun   +11 more
doaj   +1 more source

Tuberculosis in London: The importance of homelessness, problem drug use and prison [PDF]

open access: yes, 2007
Background: The control of tuberculosis (TB) is founded on early case detection and complete treatment of disease. In the UK, TB is concentrated in subgroups of the population in large urban centres.
Murad, S   +5 more
core  

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