Results 61 to 70 of about 2,722,809 (208)

Case report: A 9-year systematic treatment failure of a pulmonary tuberculosis patient

Frontiers in Public Health, 2022
ObjectiveTo explore the reasons of failure in a case of pulmonary tuberculosis (PTB) after 9 years systematic treatment.MethodsWe extracted the patients' treatment history, drug susceptibility testing (DST), Computed tomography (CT) images, and sequenced
Hui Jiang, Hui Jiang, Chendi Zhu, Chendi Zhu, Chendi Zhu, Liyi Qin, Liyi Qin, Liyi Qin, Xiaoguang Wu, Xiaoguang Wu, Jinfeng Yin, Jinfeng Yin, Jinfeng Yin, Yijia Guo, Yijia Guo, Yijia Guo, Huan Ma, Junnan Jia, Junnan Jia, Junnan Jia, Fengmin Huo, Fengmin Huo, Fengmin Huo, Yi Xue, Yi Xue, Yi Xue, Mengqiu Gao, Mengqiu Gao, Weimin Li, Weimin Li, Weimin Li   +30 more
doaj   +1 more source

The infectiousness of tuberculosis patients coinfected with HIV [PDF]

, 2008
The current understanding of airborne tuberculosis (TB) transmission is based on classic 1950s studies in which guinea pigs were exposed to air from a tuberculosis ward.
Ticona, E., Navincopa, Marcos, Gilman, RH, Gilman, R.H., Caviedes, L, Carlton A Evans, Patricia Sheen, Caviedes, L., Gilman Robert H, Gonzalez Armando, Ticona, Eduardo, Gonzalez, A, Moore, David AJ, Sheen, Patricia, Robert H Gilman, Caviedes Luz, Sheen Patricia, Armando Gonzalez, Navincopa, M., Catherine J Noakes, Sheen, P, Jon S Friedland, A Roderick Escombe, Gilman, Robert H, Martínez Carlos, Pan, W., Martinez, C, Escombe, AR, William Pan, Luz Caviedes, Evans, Carlton A, Gonzalez, A., Friedland, Jon S, Navincopa, M, Pan, W, Escombe A. Roderick, Noakes Catherine J, Noakes, Catherine J, Martínez, Carlos, Noakes, CJ, Evans, C.A., Evans, CA, Carlos Martínez, Moore, D.A.J., Caviedes, Luz, Moore, DAJ, Escombe, A.R., Friedland, J.S., Pan, William, Ticona, E, Moore David A. J, Navincopa Marcos, Pan William, David A J Moore, Friedland Jon S, Noakes, C.J., Sheen, P., Friedland, JS, Martinez, C., Ticona Eduardo, Marcos Navincopa, Evans Carlton A, Gonzalez, Armando, Eduardo Ticona, Escombe, A Roderick   +64 more
core   +2 more sources

Significant difference in Th1/Th2 paradigm induced by tuberculosis-specific antigens between IGRA-positive and IGRA-negative patients

Frontiers in Immunology, 2022
False negative interferon-γ release assay (IGRA) results constitute the major dilemma for the diagnosis of tuberculosis (TB) infections. Herein, we conducted a cohort study to compare the host immunological response to TB-specific antigens between active
Qiang Li, Weicong Ren, Jinfeng Yuan, Haiping Guo, Yuanyuan Shang, Wei Wang, Junhua Pan, Mengqiu Gao, Yu Pang   +8 more
doaj   +1 more source

The Efficacy of the Crude Root Bark Extracts of Erythrina Abyssinica on Rifampicin Resistant Mycobacterium Tuberculosis. [PDF]

, 2011
Tuberculosis (TB) is one of the leading causes of morbidity and mortality with a global mortality rate at two million deaths per year while one third of the world's population is infected with the TB bacillus.
Orodho, J.A., Bunalema, L, Bunalema, L., Kirimuhuzya, C., Orodho, J A, Tabuti, J.R., Kirimuhuzya, C, Magadula, J J, Otieno, N., Okemo, P, Otieno, N, Tabuti, JRS, Orodho, JA, Magadula, J.J., Waako, P., Tabuti, J R S, Waako, P, Magadula, JJ   +17 more
core   +1 more source

Analysis on Drug-Resistance-Associated Mutations among Multidrug-Resistant Mycobacterium tuberculosis Isolates in China

Antibiotics, 2021
As the causative bacteria of tuberculosis, Mycobacteriumtuberculosis (M. tb) is aggravated by the emergence of its multidrug-resistant isolates in China.
Hongbing Jia, Yuhui Xu, Zhaogang Sun
doaj   +1 more source

Tuberculosis in London: The importance of homelessness, problem drug use and prison [PDF]

, 2007
Background: The control of tuberculosis (TB) is founded on early case detection and complete treatment of disease. In the UK, TB is concentrated in subgroups of the population in large urban centres.
Murad, S, Story, A, Verheyen, M, London Tuberculosis Nurses Network, Hayward, AC, Roberts, W   +5 more
core  

Pulmonary Tuberculosis among People Living with HIV/AIDS Attending Care and Treatment in Rural Northern Tanzania. [PDF]

, 2008
Tuberculosis is the commonest opportunistic infection and the number one cause of death in HIV/AIDS patients in developing countries. To address the extent of the tuberculosis HIV coinfection in rural Tanzania we conducted a cross sectional study ...
Odd Morkve, Mfinanga, Sayoki Godfrey, Sayoki G Mfinanga, Bernard J Ngowi, Morkve Odd, Ngowi, Bernard J, Ngowi, Bernard J., Mfinanga Sayoki G, Bruun, Johan Nikolai, Mørkve, Odd, Mfinanga, Sayoki G, Johan N Bruun, Bruun Johan N, Morkve, Odd, Bruun, Johan N, Ngowi Bernard J   +15 more
core   +2 more sources

Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus

Microbiology Spectrum
Given the intrinsic resistance of Mycobacterium abscessus to a wide range of conventional antibiotics, it is urgent to explore new therapeutic approaches to manage this infection effectively. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), a proton pump
Jifang Zheng, Qiang Liu, Haoran Wang, Fengmin Huo, Junnan Jia, Hairong Huang, Suting Chen   +6 more
doaj   +1 more source

Managing drug resistant tuberculosis [PDF]

BMJ, 2008
#### Summary points Antituberculosis drug resistance is increasing both in the United Kingdom and internationally.1 2 It has come to greater public attention with the emergence of extensively drug resistant tuberculosis (box 1) in South Africa, where an outbreak proved rapidly fatal among people with advanced HIV infection.3 In this article we review ...
Grant, Alison, Gothard, Philip, Thwaites, Guy   +2 more
openaire   +4 more sources

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target [PDF]

, 2014
The human pathogen Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis (TB), a disease with high worldwide mortality rates. Current treatment programs are under significant threat from multi-drug and extensively-drug resistant ...
VijayaShankar Nataraj, Reynolds Robert C., Nicholas J Loman, Lloyd, AJ, Besra, Gurdyal S., Klaus Fütterer, Ballell, L, Reynolds, Robert C., Abrahams, Katherine A, Loman, Nicholas J., Hobrath Judith V., Gurcha Sudagar S., Alderwick, LJ, Abrahams, Katherine A., Gurcha, SS, Cox, Jonathan A G, Abrahams Katherine A., Hobrath, JV, Loman, Nicholas J, Carlos Alemparte, Lluis Ballell, Bhatt, Apoorva; id_orcid, Cox Jonathan A. G., Loman, NJ, Besra, GS, Reynolds, Robert C, Alemparte Carlos, Alderwick, Luke J, Gurcha, Sudagar S, Besra, Gurdyal S; id_orcid, Abrahams, KA, Besra Gurdyal S., Hobrath, Judith V, Barros, D, Robert C Reynolds, Loman Nicholas J., Bhatt, A, Ballell, Lluis, Nataraj, VijayaShankar, Lloyd, Adrian J., Apoorva Bhatt, Bhatt Apoorva, Nataraj, V, Alemparte, Carlos, Lloyd, Adrian J, Fütterer, K, Hobrath, Judith V., Veeraraghavan Usha, Cox, Jonathan A. G., Cox, JA, Barros David, Veeraraghavan, Usha, Bhatt, Apoorva, Adrian J Lloyd, Jonathan A G Cox, Usha, V, Gurdyal S Besra, David Barros, Lloyd Adrian J., Reynolds, RC, Alderwick, Luke J., Ballell Lluis, Usha Veeraraghavan, Fütterer Klaus, Barros, David, Nataraj, Vijaya-Shankar, Luke J Alderwick, Gurcha, Sudagar S., Alderwick Luke J., Judith V Hobrath, Sudagar S Gurcha, Usha, Veeraraghavan, Nataraj VijayaShankar, Alemparte, C, Fütterer, Klaus, Katherine A Abrahams   +75 more
core   +1 more source