Results 41 to 50 of about 2,897,181 (203)
International Journal of Infectious Diseases, 2020 Objectives: To compare the prevalence of levofloxacin (LFX) resistance and the population structure of Mycobacterium tuberculosis (MTB) with different mutations conferring LFX resistance between 2005 and 2015.
Fengmin Huo +8 more
doaj +1 more source
Low-cost rapid detection of rifampicin resistant tuberculosis using bacteriophage in Kampala, Uganda. [PDF]
, 2007 BACKGROUND: Resistance to anti-tuberculosis drugs is a serious public health problem. Multi-drug resistant tuberculosis (MDR-TB), defined as resistance to at least rifampicin and isoniazid, has been reported in all regions of the world.
Traore, Hamidou +38 more
core +1 more source
Light-activated nanomaterials for tumor immunotherapy
Frontiers in Chemistry, 2022 Tumor immunotherapy mainly relies on activating the immune system to achieve antitumor treatment. However, the present tumor immunotherapy used in the clinic showed low treatment efficacy with high systematic toxicity.
Fang Wang +11 more
doaj +1 more source
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial [PDF]
, 2014 Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated ...
Squire, Stephen Bertel +25 more
core +2 more sources
Bedaquiline resistance pattern in clofazimine-resistant clinical isolates of tuberculosis patients
Journal of Global Antimicrobial Resistance, 2023 : Objectives: Bedaquiline (BDQ) is a potent drug for treating drug-resistant tuberculosis (TB). Here, we analysed the resistance profiles of BDQ in CFZ-resistant clinical isolates and investigated the clinical risk factors of BDQ and CFZ cross/co ...
Yuanyuan Shang +10 more
doaj +1 more source
Tuberculosis in Sudan: a study of Mycobacterium tuberculosis strain genotype and susceptibility to anti-tuberculosis drugs. [PDF]
, 2011 BACKGROUND: Sudan is a large country with a diverse population and history of civil conflict. Poverty levels are high with a gross national income per capita of less than two thousand dollars.
Bottomley, Christian +23 more
core +2 more sources
mSystemsCentral carbon metabolism is fundamental to the growth and virulence of Mycobacterium tuberculosis (Mtb). The aceE gene encodes the E1 subunit of the pyruvate dehydrogenase complex that irreversibly converts pyruvate to acetyl-CoA. There, we investigated
Suting Chen +8 more
doaj +1 more source
Drug-Resistant Tuberculosis [PDF]
Infectious Disease Clinics of North America, 2016 Antimicrobial resistance is a natural evolutionary process, which in the case of Mycobacterium tuberculosis is based on spontaneous chromosomal mutations, meaning that well-designed combination drug regimens provided under supervised therapy will prevent the emergence of drug-resistant strains.
Sebastian G, Kurz +2 more
openaire +2 more sources
Extensively drug resistant tuberculosis in South Africa [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 161-168).There are few data for treatment-related outcomes in patients with XDR tuberculosis in settings with high HIV prevalence.
Shean, Karen Penelope
core +1 more source
Bone penetration of linezolid in osteoarticular tuberculosis patients of China
International Journal of Infectious Diseases, 2021 Background: Linezolid presents strong antimicrobial activity against multidrug-resistant (MDR) pulmonary tuberculosis (TB), but its application in osteoarticular tuberculosis treatment remains understudied.
Shu’an Wen +10 more
doaj +1 more source