Results 41 to 50 of about 2,722,809 (208)

Primary Antimicrobial Resistance Among Mycobacterium Tuberculosis Isolates from HIV Seropositive and HIV Seronegative Patients in Dar es Salaam Tanzania. [PDF]

, 2008
The United Republic of Tanzania is one of the 22 high M. tuberculosis burden countries. Data collected between 2002 and 2007 indicate that the global prevalence of drug-resistant M. tuberculosis including MDR vary greatly.
Saathoff, Elmar, Mugusi, F., Saathoff, E., Moshiro Candida, Bosch, R., Urassa, W., Urassa, Willy, Mugusi Ferdinand, Fawzi Wafaie, Villamor, E., Mugusi, Ferdinand, Moshiro, C., Fawzi, W., Bosch, Ronald, Saathoff Elmar, Bosch Ronald, Msamanga Gernard, Msamanga, Gernard, Moshiro, Candida, Villamor Eduardo, Villamor, Eduardo, Fawzi, Wafaie, Urassa Willy   +22 more
core   +1 more source

Xpert MTB/RIF Ultra outperformed the Xpert assay in tuberculosis lymphadenitis diagnosis: a prospective head-to-head cohort study

International Journal of Infectious Diseases, 2022
Objectives: Xpert Mycobacterium tuberculosis/rifampin (MTB/RIF) Ultra (Xpert-Ultra) has shown better sensitivity in comparison with Xpert MTB/RIF (Xpert) in extrapulmonary tuberculosis (TB), whereas the head-to-head comparison of these methods in TB ...
Xia Yu, Tingting Zhang, Yaoyao Kong, Fen Wang, Lingling Dong, Ming Han, Hairong Huang   +6 more
doaj   +1 more source

Tuberculosis in Sudan: a study of Mycobacterium tuberculosis strain genotype and susceptibility to anti-tuberculosis drugs. [PDF]

, 2011
BACKGROUND: Sudan is a large country with a diverse population and history of civil conflict. Poverty levels are high with a gross national income per capita of less than two thousand dollars.
Bottomley, Christian, McNerney Ruth, Ali Ahmed B, Salih, Abdel Latif Ga, McNerney, Ruth, Mohammed S Ali, Ruth McNerney, Fadl-Elmula, Imad, Christian Bottomley, Ali, Ahmed B, Ghada S Sharaf Eldin, Imad Fadl-Elmula, Ali, Mohammed S, Mallard, Kim, Abdel Latif GA Salih, Bottomley Christian, Ahmed B Ali, Salih Abdel Latif GA, Fadl-Elmula Imad, Sharaf Eldin, Ghada S, Ali Mohammed S, Kim Mallard, Sharaf Eldin Ghada S, Mallard Kim   +23 more
core   +2 more sources

Increased prevalence of levofloxacin-resistant Mycobacterium tuberculosis in China is associated with specific mutations within the gyrA gene

International Journal of Infectious Diseases, 2020
Objectives: To compare the prevalence of levofloxacin (LFX) resistance and the population structure of Mycobacterium tuberculosis (MTB) with different mutations conferring LFX resistance between 2005 and 2015.
Fengmin Huo, Fuzhen Zhang, Yi Xue, Yuanyuan Shang, Qian Liang, Yifeng Ma, Yunxu Li, Liping Zhao, Yu Pang   +8 more
doaj   +1 more source

Drug Resistance in Tuberculosis

Annals of Saudi Medicine, 1990
Resistance to antituberculosis drugs is due to the occurrence of resistant mutants in the bacterial population even before exposure to these drugs. These mutations are chromosomal in origin. Resistance occurs when the bacterial population is large or when drugs are used alone. Potent drugs such as rifampicin, isoniazid and streptomycin are effective in
openaire   +2 more sources

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Rose, PC, Hallbauer, UM, Hesseling, AC, Schaaf, HS, Seddon, JA   +4 more
core   +1 more source

Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial [PDF]

, 2014
Background In contrast to drug-sensitive tuberculosis, the guidelines for the treatment of multi-drug-resistant tuberculosis (MDR-TB) have a very poor evidence base; current recommendations, based on expert opinion, are that patients should be treated ...
Squire, Stephen Bertel, Squire, S Bertel, Patrick PJ Phillips, Madan, Jason, Rusen, I. D., Chiang, Chen-Yuan, Armand Van Deun, Chiang, Chen Yuan, Gabriela Torrea, Phillips, P. (Patrick), Van Deun, Armand, Rusen, ID, Meredith, Sarah K, Jason Madan, Meredith, Sarah K., Nunn, Andrew J, ID Rusen, Nunn, Andrew J., Squire, Bertie, Torrea, Gabriela, Chen-Yuan Chiang, Sarah K Meredith, Phillips, Patrick PJ, Andrew J Nunn, Phillips, Patrick P.J., S Bertel Squire   +25 more
core   +2 more sources

Light-activated nanomaterials for tumor immunotherapy

Frontiers in Chemistry, 2022
Tumor immunotherapy mainly relies on activating the immune system to achieve antitumor treatment. However, the present tumor immunotherapy used in the clinic showed low treatment efficacy with high systematic toxicity.
Fang Wang, Fang Wang, Huijuan Duan, Huijuan Duan, Weizhe Xu, Weizhe Xu, Gang Sheng, Gang Sheng, Zhaogang Sun, Zhaogang Sun, Hongqian Chu, Hongqian Chu   +11 more
doaj   +1 more source

Treatment of Drug-Resistant Tuberculosis [PDF]

Clinics in Chest Medicine, 2019
The treatment of drug-resistant tuberculosis (TB) is complicated and has evolved significantly in the past decade with the advent of rapid molecular tests and updated evidence-based guidelines of the World Health Organization and other organizations.
Sundari R, Mase, Terence, Chorba
openaire   +2 more sources

Bedaquiline resistance pattern in clofazimine-resistant clinical isolates of tuberculosis patients

Journal of Global Antimicrobial Resistance, 2023
: Objectives: Bedaquiline (BDQ) is a potent drug for treating drug-resistant tuberculosis (TB). Here, we analysed the resistance profiles of BDQ in CFZ-resistant clinical isolates and investigated the clinical risk factors of BDQ and CFZ cross/co ...
Yuanyuan Shang, Suting Chen, Wenhui Shi, Wenjuan Nie, Wei Jing, Fengmin Huo, Yi Xue, Lingling Dong, Guanglu Jiang, Hairong Huang, Naihui Chu   +10 more
doaj   +1 more source