Results 21 to 30 of about 86,450 (250)

EasyNAT MTC assay: A simple, rapid, and low-cost cross-priming amplification method for the detection of mycobacterium tuberculosis suitable for point-of-care testing

open access: yesEmerging Microbes and Infections, 2021
More sensitive, rapid, and affordable diagnostic tools for pulmonary tuberculosis (PTB) are urgently needed. This study aimed to assess the performance of EasyNAT MTC (abbreviation: EasyNAT) (Ustar Biotechnologies, China), a novel isothermal ...
Zhuman Zhang   +10 more
doaj   +1 more source

Drug Resistance in Tuberculosis [PDF]

open access: yesJournal of Tropical Pediatrics, 2007
Tuberculosis (TB) kills about 2 million adults and around 100 000 children every year. One-third of the worlds population are currently infected with Mycobacterium tuberculosis and many have active disease. In Europe TB emerged as a major disease in the latter part of the 14th century.
openaire   +2 more sources

GeneXpert MTB/RIF assay in the diagnosis of urinary tuberculosis from urine specimens

open access: yesScientific Reports, 2017
Conventional bacteriological methods are not generally helpful in diagnosing urinary tuberculosis (UTB). GeneXpert is endorsed for the detection of pulmonary tuberculosis, whereas the data on its utility for urine specimens is limited.
Yu Pang   +8 more
doaj   +1 more source

Biological interpretation of the sporadic sputum smear-positive-culture-negative outcome for patients with tuberculosis undertaking treatments

open access: yesFrontiers in Public Health, 2023
IntroductionThe objective of the study was to identify the causes of smear-positive-culture-negative (S+/C–) outcomes of patients with tuberculosis during the treatment course.MethodsA laboratory-based retrospective study was performed at the Beijing ...
Jingjing Luo   +9 more
doaj   +1 more source

Treatment of drug-resistant tuberculosis

open access: yesInfection and Drug Resistance, 2011
What is the best approach to the treatment of drug-resistant tuberculosis (TB)?Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively ...
Pinto,Lancelot, Menzies,Dick
openaire   +6 more sources

Xpert MTB/RIF Ultra outperformed the Xpert assay in tuberculosis lymphadenitis diagnosis: a prospective head-to-head cohort study

open access: yesInternational Journal of Infectious Diseases, 2022
Objectives: Xpert Mycobacterium tuberculosis/rifampin (MTB/RIF) Ultra (Xpert-Ultra) has shown better sensitivity in comparison with Xpert MTB/RIF (Xpert) in extrapulmonary tuberculosis (TB), whereas the head-to-head comparison of these methods in TB ...
Xia Yu   +6 more
doaj   +1 more source

Drug resistance in tuberculosis [PDF]

open access: yesEuropean Respiratory Journal, 2005
A drug-resistant strain ofMycobacterium tuberculosisis defined as one differing from the tight distribution of wild strains that have not come into contact with the drug concerned.Sensitivity tests are performed by the absolute concentration method, the resistance ratio method or the proportion method. The hypothesis underlying the proportion method is
openaire   +2 more sources

Increased prevalence of levofloxacin-resistant Mycobacterium tuberculosis in China is associated with specific mutations within the gyrA gene

open access: yesInternational Journal of Infectious Diseases, 2020
Objectives: To compare the prevalence of levofloxacin (LFX) resistance and the population structure of Mycobacterium tuberculosis (MTB) with different mutations conferring LFX resistance between 2005 and 2015.
Fengmin Huo   +8 more
doaj   +1 more source

Characterization of Mycobacterium tuberculosis strains in Beijing, China: drug susceptibility phenotypes and Beijing genotype family transmission

open access: yesBMC Infectious Diseases, 2018
Background The most prevalent strains of Mycobacterium tuberculosis (M.tb) in Beijing belong to the Beijing genotype family. The influence of Beijing genotype prevalence on the development of drug resistance, and the association of infection with Beijing
Yi Liu   +6 more
doaj   +1 more source

Light-activated nanomaterials for tumor immunotherapy

open access: yesFrontiers in Chemistry, 2022
Tumor immunotherapy mainly relies on activating the immune system to achieve antitumor treatment. However, the present tumor immunotherapy used in the clinic showed low treatment efficacy with high systematic toxicity.
Fang Wang   +11 more
doaj   +1 more source

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