Results 21 to 30 of about 2,897,181 (203)

Drug-resistant tuberculosis

The Lancet, 1993
Multidrug-resistant tuberculosis (MDRTB) is an iatrogenic disease that is emerging as a major infectious disease problem throughout the world. The AIDS pandemic, increased incidence of tuberculosis in populations with easy access to antituberculosis medications, the deterioration of the public health infrastructure, and inadequate training of health ...
B A, Hanna, S, Bonk, L K, Tick
openaire   +4 more sources

Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. [PDF]

, 2012
SETTING AND OBJECTIVE: To describe trends in drug-resistant tuberculosis (TB) in two gold-mining workforces, South Africa, 2002-2008. DESIGN: TB programme data analysis.
Fielding, K. L., van Halsema, CL, Churchyard, GJ, Churchyard, G. J., Chihota, VN, Grant, AD, Chihota, V. N., Grant, A. D., Fielding, KL, van Halsema, C. L., Lewis, J. J., Lewis, JJ   +11 more
core   +1 more source

The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis. [PDF]

, 2019
The Lancet Respiratory Medicine Commission on drug-resistant tuberculosis was published in 2017, which comprehensively reviewed and provided recommendations on various aspects of the disease.
Dowdy, David, Nuermberger, Eric, Chang, Kwok Chiu, Migliori, G.B., Furin, Jennifer, Limberis, Jason, Menzies, Dick, McIlleron, Helen, Jindani, Amina, Jaramillo, Ernesto, McNerney, Ruth, Nardell, Edward A., Dooley, Kelly E., Schaaf, H. Simon, Barry, Clifton E., Van Rie, Annelies, Ndjeka, Norbert, Keshavjee, Salmaan, Rodrigues, Camilla, Low, Marcus, Lange, Christoph, Padayatchi, Nesri, Nahid, Payam, Nunn, Andrew, Sirgel, Frik A., Warren, Robin M., Udwadia, Zarir F., Lessem, Erica, Maartens, Gary, Horsburgh, C. Robert, Esmail, Aliasgar, Clark, Taane G., Murray, Megan, Seddon, James A., Pasipanodya, Jotam G., Gumbo, Tawanda, Niemann, Stefan, Dheda, Keertan, Churchyard, Gavin J., London, Leslie, Theron, Grant, Fourie, Bernard, Fennelly, Kevin P., Hesseling, Anneke C., Murray, M, Warren, RM, Furin, J, Dooley, KE, Dheda, K, Nardell, EA, Maartens, G, Gumbo, T, Lancet Respiratory Medicine drug-resistant tuberculosis Commissi   +52 more
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Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S., Siba Peter, Beck, H. P., Hans-Peter Beck, Beck Hans-Peter, Carter Robyn, Paul Harino, Harino, P., Carter, R., Serej Ley, Ley Serej, Siba, P., Gagneux Sebastien, Borrell Sonia, Coscolla Mireia, Mireia Coscolla, Ballif Marie, Stefan Niemann, Ley, S., Marie Ballif, Coulter, C., Robyn Carter, Coulter Christopher, Christopher Coulter, Ballif, M., Peter Siba, Niemann, S., Harino Paul, Niemann Stefan, Sebastien Gagneux, Phuanukoonnon, S., Borrell, S., Coscolla, M., Sonia Borrell, Suparat Phuanukoonnon, Phuanukoonnon Suparat, Ballif M, Gagneux S, Harino P, Carter R, Borrell S, Coulter C, Niemann S, Beck HP, Phuanukoonnon S, Ley S, Siba P, Coscolla M   +47 more
core   +1 more source

New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections [PDF]

, 2008
Tuberculosis remains the most common cause of death due to a single infective organism. Despite the availability of a vaccine and chemotherapeutic options, the global disease burden remains relatively unaffected.
Willcox, Benjamin, Gurdyal S Besra, Bhatt, Apoorva; id_orcid, Dover, LG, Apoorva Bhatt, Dover, Lynn, Besra, Gurdyal; id_orcid, Besra, Gurdyal, Bhatt, Apoorva, Lynn G Dover, Bhowruth, Veemal, Veemal Bhowruth, Benjamin E Willcox   +12 more
core   +1 more source

Synthesis, antitubercular activity and mechanism of resistance of highly effective thiacetazone analogues [PDF]

, 2013
Defining the pharmacological target(s) of currently used drugs and developing new analogues with greater potency are both important aspects of the search for agents that are effective against drug-sensitive and drug-resistant Mycobacterium tuberculosis ...
Derek Craig, Rosa Milagros Corrales, Craig Derek, Gannoun-Zaki, Laila, Geoffrey D Coxon, Laila Gannoun-Zaki, Laurent Kremer, Gannoun-Zaki Laila, Emilie Vialla, Coxon, Geoffrey, Corrales, Rosa Milagros, Coxon Geoffrey D., Vialla, Emilie, Kremer Laurent, Kremer, Laurent, Corrales Rosa Milagros, Vialla Emilie, Craig, Derek   +17 more
core   +5 more sources

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney, van Helden, Paul D., Nicolaas C. Gey van Pittius (173264), Paul D. van Helden (33594), Marlein E Bosman, Gagneux, Sebastien, Thomas C Victor, Manormoney Pillay (257769), Nicolaas C Gey van Pittius, Borna Müller (173253), Hayes, Cindy, Streicher, Elizabeth M., Andre Trollip (449922), Robin M Warren, Elizabeth M Streicher, Trollip, Andre, Violet N. Chihota (143307), Warren, Robin M., Bosman, Marlein E., Müller, Borna, Violet N Chihota, Cindy Hayes, Marisa Klopper (398815), Cindy Hayes (449923), Elizabeth M. Streicher (439727), Borna Müller, Paul D van Helden, Marlein E. Bosman (449924), Klopper, Marisa, Gerrit Coetzee, Sebastien Gagneux (149824), Chihota, Violet N., Andre Trollip, Marisa Klopper, Sebastien Gagneux, Gerrit Coetzee (296078), Victor, Thomas C., Manormoney Pillay, Coetzee, Gerrit, Gey van Pittius, Nicolaas C., Robin M. Warren (33593), Thomas C. Victor (185348), Pillay M, Klopper Marisa, Warren Robin M., van Helden PD, Trollip A, Streicher EM, Victor Thomas C., Coetzee Gerrit, Gey van Pittius NC, Chihota VN, Müller Borna, Warren RM, Hayes C, Gagneux Sebastien, Gagneux S, Streicher Elizabeth M., Trollip Andre, Müller B, Coetzee G, Gey van Pittius Nicolaas C., Bosman Marlein E., Pillay Manormoney, Chihota Violet N., van Helden Paul D., Victor TC, Hayes Cindy, Bosman ME, Klopper M   +69 more
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Exploring prospects of novel drugs for tuberculosis [PDF]

, 2012
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However, even for the treatment of drug-sensitive tuberculosis,
Pieters, J., Janssen, S., Grobusch, M. P., Khathi, L., Jayachandran, R., Zinsstag, J., Grobusch, Martin   +6 more
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In Vitro Activity of the Sudapyridine (WX-081) against Non-Tuberculous Mycobacteria Isolated in Beijing, China

Microbiology Spectrum, 2022
Sudapyridine (WX-081) is a structural analog of bedaquiline (BDQ), which shows an anti-tuberculosis activity but, unlike BDQ, did not prolong QT interval (QT) in animal model studies.
Rui Zhu, Yuanyuan Shang, Suting Chen, Hua Xiao, Ruyan Ren, Fen Wang, Yi Xue, Lei Li, Yongguo Li, Naihui Chu, Hairong Huang   +10 more
doaj   +1 more source

International spread of MDR TB from Tugela Ferry, South Africa. [PDF]

, 2011
We describe a death associated with multidrug-resistant tuberculosis and HIV infection outside Africa that can be linked to Tugela Ferry (KwaZulu-Natal, South Africa), the town most closely associated with the regional epidemic of drug-resistant ...
Beaton, R Kate, John, Laurence, Simon Ashworth, Onn Kon, Alexander Pym, O. Martin Williams, Kon, Onn Min, Richard J. Lessells, Alexander S. Pym, Williams, O Martin, Graham Cooke, Pym, Alexander S, Onn Min Kon, Graham S. Cooke, Cooke, Graham S, Moodley, P, Supply, P, R. Kate Beaton, P. Supply, Laurence John, Lessells, Richard J, Ashworth, Simon, Richard Lessells, P. Moodley   +23 more
core   +1 more source