Results 21 to 30 of about 86,450 (250)
More sensitive, rapid, and affordable diagnostic tools for pulmonary tuberculosis (PTB) are urgently needed. This study aimed to assess the performance of EasyNAT MTC (abbreviation: EasyNAT) (Ustar Biotechnologies, China), a novel isothermal ...
Zhuman Zhang +10 more
doaj +1 more source
Drug Resistance in Tuberculosis [PDF]
Tuberculosis (TB) kills about 2 million adults and around 100 000 children every year. One-third of the worlds population are currently infected with Mycobacterium tuberculosis and many have active disease. In Europe TB emerged as a major disease in the latter part of the 14th century.
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GeneXpert MTB/RIF assay in the diagnosis of urinary tuberculosis from urine specimens
Conventional bacteriological methods are not generally helpful in diagnosing urinary tuberculosis (UTB). GeneXpert is endorsed for the detection of pulmonary tuberculosis, whereas the data on its utility for urine specimens is limited.
Yu Pang +8 more
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IntroductionThe objective of the study was to identify the causes of smear-positive-culture-negative (S+/C–) outcomes of patients with tuberculosis during the treatment course.MethodsA laboratory-based retrospective study was performed at the Beijing ...
Jingjing Luo +9 more
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Treatment of drug-resistant tuberculosis
What is the best approach to the treatment of drug-resistant tuberculosis (TB)?Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively ...
Pinto,Lancelot, Menzies,Dick
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Objectives: Xpert Mycobacterium tuberculosis/rifampin (MTB/RIF) Ultra (Xpert-Ultra) has shown better sensitivity in comparison with Xpert MTB/RIF (Xpert) in extrapulmonary tuberculosis (TB), whereas the head-to-head comparison of these methods in TB ...
Xia Yu +6 more
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Drug resistance in tuberculosis [PDF]
A drug-resistant strain ofMycobacterium tuberculosisis defined as one differing from the tight distribution of wild strains that have not come into contact with the drug concerned.Sensitivity tests are performed by the absolute concentration method, the resistance ratio method or the proportion method. The hypothesis underlying the proportion method is
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Objectives: To compare the prevalence of levofloxacin (LFX) resistance and the population structure of Mycobacterium tuberculosis (MTB) with different mutations conferring LFX resistance between 2005 and 2015.
Fengmin Huo +8 more
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Background The most prevalent strains of Mycobacterium tuberculosis (M.tb) in Beijing belong to the Beijing genotype family. The influence of Beijing genotype prevalence on the development of drug resistance, and the association of infection with Beijing
Yi Liu +6 more
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Light-activated nanomaterials for tumor immunotherapy
Tumor immunotherapy mainly relies on activating the immune system to achieve antitumor treatment. However, the present tumor immunotherapy used in the clinic showed low treatment efficacy with high systematic toxicity.
Fang Wang +11 more
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