Results 11 to 20 of about 2,897,181 (203)

Treatment of drug-resistant tuberculosis

Infection and Drug Resistance, 2011
What is the best approach to the treatment of drug-resistant tuberculosis (TB)?Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively ...
Pinto,Lancelot, Menzies,Dick
core   +7 more sources

Drug resistant tuberculosis [PDF]

BMJ, 1995
EDITOR,—Concern is growing over the spread of drug resistant Mycobacterium tuberculosis. New evidence suggests that this spread may be increasing in certain sections of the British population. The recent advances in molecular techniques have equipped us with the means to make substantial inroads into the possible impact of drug resistant tuberculosis.1
openaire   +6 more sources

Extensively drug-resistant tuberculosis [PDF]

Current Opinion in Infectious Diseases, 2009
To describe the origin, epidemiology, diagnosis, treatment, prevention, and control of extensively drug-resistant tuberculosis (XDR TB).XDR TB is defined as the occurrence of TB in persons whose Mycobacterium tuberculosis isolates are resistant to isoniazid and rifampin and to any fluoroquinolone and at least one of three injectable second-line drugs ...
Mandeep, Jassal, William R, Bishai
openaire   +4 more sources

Comparison of the in vitro activity of linezolid, tedizolid, sutezolid, and delpazolid against rapidly growing mycobacteria isolated in Beijing, China

International Journal of Infectious Diseases, 2021
Background: The natural resistance of rapidly growing mycobacteria (RGM) to multiple antibiotics renders the treatment of the infections caused less successful.
Shu’an Wen, Xiaopan Gao, Weijie Zhao, Fengmin Huo, Guanglu Jiang, Lingling Dong, Liping Zhao, Fen Wang, Xia Yu, Hairong Huang   +9 more
doaj   +1 more source

The aceE involves in mycolic acid synthesis and biofilm formation in Mycobacterium smegmatis

BMC Microbiology, 2020
Background The integrity of cell wall structure is highly significant for the in vivo survival of mycobacteria. We hypothesized that changes in morphology may indicate changes in cell wall metabolism and identified an aceE gene mutant (aceE-mut) which ...
Suting Chen, Tianlu Teng, Shuan Wen, Tingting Zhang, Hairong Huang   +4 more
doaj   +1 more source

Extremely high levels of central nervous system involvement in miliary tuberculosis

BMC Infectious Diseases, 2022
Background Miliary tuberculosis (TB) is one of the severest manifestations of TB that can be lethal when concomitant with the central nervous system (CNS) involvement.
Guirong Wang, Ruixia Liang, Qing Sun, Xinlei Liao, Chenqian Wang, Hairong Huang   +5 more
doaj   +1 more source

Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens

Microbiology Spectrum, 2022
Next-generation sequencing (NGS) enables rapid identification of common and rare drug-resistant genetic variations from tuberculosis (TB) patients’ sputum samples and MTB isolates.
Jing Song, Weili Du, Zichen Liu, Jialu Che, Kun Li, Nanying Che   +5 more
doaj   +1 more source

Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]

, 2004
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR, Story, A, Hayward, AC, Watson, JM, Conaty, SJ, Drobniewski, FA   +5 more
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Non-tuberculous mycobacterial disease: progress and advances in the development of novel candidate and repurposed drugs

Frontiers in Cellular and Infection Microbiology, 2023
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens that can infect all body tissues and organs. In particular, the lungs are the most commonly involved organ, with NTM pulmonary diseases causing serious health issues in patients with ...
Yuzhen Gu, Wenjuan Nie, Hairong Huang, Xia Yu   +3 more
doaj   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth, McNerney Ruth, Zager Ellen M   +3 more
core   +1 more source