Results 11 to 20 of about 2,722,809 (208)

Treatment of drug-resistant tuberculosis

The Lancet Infectious Diseases, 2011
What is the best approach to the treatment of drug-resistant tuberculosis (TB)?Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively ...
Kanchan, Ajbani, Rajeev, Soman, Anjali, Shetty, Camilla, Rodrigues   +3 more
core   +7 more sources

Xpert MTB/RIF Ultra Assay Using Stool: an Effective Solution for Bacilli Identification from Adult Pulmonary Tuberculosis Suspects without Expectorated Sputum

Microbiology Spectrum, 2023
This study evaluated the diagnostic performance of stool-based Xpert MTB/RIF Ultra assay (Xpert-Ultra, Cepheid, USA) against other tests using respiratory tract specimens (RTS) and stool for diagnosing adult pulmonary tuberculosis. A prospective study on
Xia Yu, Fen Wang, Ruyan Ren, Lingling Dong, Yi Xue, Liping Zhao, Junnan Jia, Hairong Huang   +7 more
doaj   +1 more source

Trends and Species Diversity of Non-tuberculous Mycobacteria Isolated From Respiratory Samples in Northern China, 2014–2021

Frontiers in Public Health, 2022
BackgroundPulmonary non-tuberculous mycobacteria (NTM) infection has become a public health concern in China and around the world. The objective of this study was to describe the longitudinal changes in the frequency and diversity of NTM in northern ...
Qing Sun, Jun Yan, Xinlei Liao, Chaohong Wang, Chenqian Wang, Guanglu Jiang, Lingling Dong, Fen Wang, Hairong Huang, Guirong Wang, Junhua Pan   +10 more
doaj   +1 more source

Comparison of the in vitro activity of linezolid, tedizolid, sutezolid, and delpazolid against rapidly growing mycobacteria isolated in Beijing, China

International Journal of Infectious Diseases, 2021
Background: The natural resistance of rapidly growing mycobacteria (RGM) to multiple antibiotics renders the treatment of the infections caused less successful.
Shu’an Wen, Xiaopan Gao, Weijie Zhao, Fengmin Huo, Guanglu Jiang, Lingling Dong, Liping Zhao, Fen Wang, Xia Yu, Hairong Huang   +9 more
doaj   +1 more source

The aceE involves in mycolic acid synthesis and biofilm formation in Mycobacterium smegmatis

BMC Microbiology, 2020
Background The integrity of cell wall structure is highly significant for the in vivo survival of mycobacteria. We hypothesized that changes in morphology may indicate changes in cell wall metabolism and identified an aceE gene mutant (aceE-mut) which ...
Suting Chen, Tianlu Teng, Shuan Wen, Tingting Zhang, Hairong Huang   +4 more
doaj   +1 more source

Non-tuberculous mycobacterial disease: progress and advances in the development of novel candidate and repurposed drugs

Frontiers in Cellular and Infection Microbiology, 2023
Non-tuberculous mycobacteria (NTM) are opportunistic pathogens that can infect all body tissues and organs. In particular, the lungs are the most commonly involved organ, with NTM pulmonary diseases causing serious health issues in patients with ...
Yuzhen Gu, Wenjuan Nie, Hairong Huang, Xia Yu   +3 more
doaj   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth, McNerney Ruth, Zager Ellen M   +3 more
core   +1 more source

Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens

Microbiology Spectrum, 2022
Next-generation sequencing (NGS) enables rapid identification of common and rare drug-resistant genetic variations from tuberculosis (TB) patients’ sputum samples and MTB isolates.
Jing Song, Weili Du, Zichen Liu, Jialu Che, Kun Li, Nanying Che   +5 more
doaj   +1 more source

Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]

, 2004
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR, Story, A, Hayward, AC, Watson, JM, Conaty, SJ, Drobniewski, FA   +5 more
core   +1 more source

Trends in drug-resistant tuberculosis in a gold-mining workforce in South Africa, 2002-2008. [PDF]

, 2012
SETTING AND OBJECTIVE: To describe trends in drug-resistant tuberculosis (TB) in two gold-mining workforces, South Africa, 2002-2008. DESIGN: TB programme data analysis.
Fielding, K. L., van Halsema, CL, Churchyard, GJ, Churchyard, G. J., Chihota, VN, Grant, AD, Chihota, V. N., Grant, A. D., Fielding, KL, van Halsema, C. L., Lewis, J. J., Lewis, JJ   +11 more
core   +1 more source