Results 81 to 90 of about 6,956,165 (310)

Institutionalizing Innovation: The New York Drug Court Story [PDF]

open access: yes, 2000
The article begins by discussing the problems that drug use is causing in the American Criminal Justice System. The article then discusses the use of drug courts, which have proven effective in reducing drug use and recidivism.
Berman, Greg   +2 more
core   +1 more source

Synergistic drug combinations from electronic health records and gene expression. [PDF]

open access: yes, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William   +19 more
core   +2 more sources

Drug–drug–gene interactions and adverse drug reactions [PDF]

open access: yesThe Pharmacogenomics Journal, 2019
AbstractThe economic and health burden caused by adverse drug reactions has increased dramatically in the last few years. This is likely to be mediated by increasing polypharmacy, which increases the likelihood for drug–drug interactions. Tools utilized by healthcare practitioners to flag potential adverse drug reactions secondary to drug–drug ...
Malki, Mustafa Adnan   +1 more
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Impact of Training High School Female Students in Ahvaz, Iran in the Social Skills Required to Avoid the Use of Drugs

open access: yesElectronic Physician, 2016
Introduction: Gender composition and the soaring trends of drug and tobacco dependency reveal the priority of social skills training related to drug avoidance self-efficacy among female students.
Freshteh Zamani Alavijeh   +4 more
doaj   +1 more source

Review of COVID-19 treatment

open access: yesJournal of Research in Pharmacy Practice, 2020
Many contagious diseases, such as plague or cholera, played a role in changing the pathway of history. In this respect, although coronavirus was not as dangerous as novel diseases such as swine flu and Ebola, the spread and the power of coronavirus ...
Somayeh Sadeghi   +3 more
doaj   +1 more source

Drug-drug interaction prediction based on co-medication patterns and graph matching [PDF]

open access: yesarXiv, 2019
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are developed within support vector machines for the prediction.
arxiv  

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Drug Distribution and Stent Retention of Drug Eluting Stents [PDF]

open access: yes, 2008
In this paper the examinations of drug eluting coronary stents are shown, such as the morphology of the coatings before expansion, drug distribution, the methodology and the value of stent retention.
Balázs, T.   +3 more
core  

Advanced modification of drug nanocrystals by using novel fabrication and downstream approaches for tailor-made drug delivery [PDF]

open access: yes, 2019
Drug nanosuspensions/nanocrystals have been recognized as one useful and successful approach for drug delivery. Drug nanocrystals could be further decorated to possess extended functions (such as controlled release) and designed for special in vivo ...
Haipeng, Yin   +3 more
core   +1 more source

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