National Institute on Drug Abuse Strategic Plan on Reducing Health Disparities [PDF]
Unlike other diseases, drug addiction poses many peculiar challenges to health researchers, providers, and public health officials in the search for effective prevention and treatment strategies and policies.
National Institute, on Drug Abuse
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Individual and Environmental Factors Associated with Tobacco Smoking, Alcohol Abuse and Illegal Drug Consumption in University Students: A Mediating Analysis [PDF]
[Abstract] Substance abuse is a major and prevalent public health concern among university students. Tobacco smoking, risky alcohol behavior, and illegal drug consumption may lead to health problems and behavioral and academic issues. Several individual
Cruz Valiño, José Manuel +6 more
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We recently reported an economic choice task in which squirrel monkeys chose between differing amounts of remifentanil, a fast-acting opioid, or a food reward to develop a preclinical screen for evaluating potential pharmacotherapies for opioid ...
Alishan S. Amirali +9 more
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Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania +3 more
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Midbrain dopamine neurons are implicated in motivation and learning. However, it is unclear how phasic excitation of dopamine neurons, which is implicated in learning, is involved in motivation.
Anton eIlango +4 more
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Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use +3 more
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Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor
D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Hideaki Yano +9 more
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Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior
Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown.
Juan L. Gomez +16 more
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Functional Connectivity Hubs and Networks in the Awake Marmoset Brain
In combination with advances in analytical methods, resting-state fMRI is allowing unprecedented access to achieve a better understanding of the network organization of the brain. Increasing evidence suggests that this architecture may incorporate highly
Annabelle Marie Belcher +10 more
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Ecological factors and adolescent marijuana use: results of a prospective study in Santiago, Chile [PDF]
PURPOSE: Despite the growing evidence that ecological factors contribute to substance use, the relationship of ecological factors and illicit drugs such as marijuana use is not well understood, particularly among adolescents in Latin America.
Andrade, Fernando H. +6 more
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