Results 11 to 20 of about 932,717 (306)

National Institute on Drug Abuse Strategic Plan on Reducing Health Disparities [PDF]

open access: yes, 2002
Unlike other diseases, drug addiction poses many peculiar challenges to health researchers, providers, and public health officials in the search for effective prevention and treatment strategies and policies.
National Institute, on Drug Abuse
core   +2 more sources

Individual and Environmental Factors Associated with Tobacco Smoking, Alcohol Abuse and Illegal Drug Consumption in University Students: A Mediating Analysis [PDF]

open access: yes, 2020
[Abstract] Substance abuse is a major and prevalent public health concern among university students. Tobacco smoking, risky alcohol behavior, and illegal drug consumption may lead to health problems and behavioral and academic issues. Several individual
Cruz Valiño, José Manuel   +6 more
core   +1 more source

Effects of buprenorphine, methadone, and cariprazine on economic choice between remifentanil and food in squirrel monkeys

open access: yesAddiction Neuroscience, 2023
We recently reported an economic choice task in which squirrel monkeys chose between differing amounts of remifentanil, a fast-acting opioid, or a food reward to develop a preclinical screen for evaluating potential pharmacotherapies for opioid ...
Alishan S. Amirali   +9 more
doaj   +1 more source

Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]

open access: yes, 2019
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania   +3 more
core   +4 more sources

Phasic excitation of ventral tegmental dopamine neurons potentiates the initiation of conditioned approach behavior: Parametric and reinforcement-schedule analyses

open access: yesFrontiers in Behavioral Neuroscience, 2014
Midbrain dopamine neurons are implicated in motivation and learning. However, it is unclear how phasic excitation of dopamine neurons, which is implicated in learning, is involved in motivation.
Anton eIlango   +4 more
doaj   +1 more source

Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]

open access: yes, 2015
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use   +3 more
core   +1 more source

Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor

open access: yesNature Communications, 2018
D1-like dopamine receptors are coupled to Golf proteins in the dorsal striatum but Gs in cortical and other areas. Here, the authors demonstrate selective agonism of Gs-coupled versus Golf-coupled D1 receptors.
Hideaki Yano   +9 more
doaj   +1 more source

Synaptic Zn2+ potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior

open access: yesTranslational Psychiatry, 2021
Cocaine binds to the dopamine (DA) transporter (DAT) to regulate cocaine reward and seeking behavior. Zinc (Zn2+) also binds to the DAT, but the in vivo relevance of this interaction is unknown.
Juan L. Gomez   +16 more
doaj   +1 more source

Functional Connectivity Hubs and Networks in the Awake Marmoset Brain

open access: yesFrontiers in Integrative Neuroscience, 2016
In combination with advances in analytical methods, resting-state fMRI is allowing unprecedented access to achieve a better understanding of the network organization of the brain. Increasing evidence suggests that this architecture may incorporate highly
Annabelle Marie Belcher   +10 more
doaj   +1 more source

Ecological factors and adolescent marijuana use: results of a prospective study in Santiago, Chile [PDF]

open access: yes, 2014
PURPOSE: Despite the growing evidence that ecological factors contribute to substance use, the relationship of ecological factors and illicit drugs such as marijuana use is not well understood, particularly among adolescents in Latin America.
Andrade, Fernando H.   +6 more
core   +2 more sources

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