Results 11 to 20 of about 4,201,815 (397)

Smoke, alcohol and drug addiction and male fertility [PDF]

open access: yesReproductive Biology and Endocrinology, 2018
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
A. Sansone   +7 more
semanticscholar   +3 more sources

Attachment Theory and Maternal Drug Addiction: The Contribution to Parenting Interventions [PDF]

open access: yesFrontiers in Psychiatry, 2016
Children’s emotional and relational development can be negatively influenced by maternal substance abuse, particularly through a dysfunctional caregiving environment.
Micol Parolin, A. Simonelli
semanticscholar   +4 more sources

Medication overuse and drug addiction: a narrative review from addiction perspective

open access: yesThe Journal of Headache and Pain, 2021
Chronic headache is particularly prevalent in migraineurs and it can progress to a condition known as medication overuse headache (MOH). MOH is a secondary headache caused by overuse of analgesics or other medications such as triptans to abort acute ...
T. Takahashi   +18 more
semanticscholar   +1 more source

Effects and associated transcriptomic landscape changes of methamphetamine on immune cells

open access: yesBMC Medical Genomics, 2022
Background Methamphetamine (METH) abuse causes serious health problems, including injury to the immune system, leading to increased incidence of infections and even making withdrawal more difficult.
Deshenyue Kong   +9 more
doaj   +1 more source

Prognostic plasma exosomal microRNA biomarkers in patients with substance use disorders presenting comorbid with anxiety and depression

open access: yesScientific Reports, 2021
Psychiatric disorders such as anxiety and depression precipitated by substance use occurred during both use and withdrawal. Exosomes play significant roles in biological functions and regulate numerous physiological and pathological processes in various ...
Fengrong Chen   +13 more
doaj   +1 more source

Methamphetamine and HIV-Tat Protein Synergistically Induce Oxidative Stress and Blood-Brain Barrier Damage via Transient Receptor Potential Melastatin 2 Channel

open access: yesFrontiers in Pharmacology, 2021
Synergistic impairment of the blood-brain barrier (BBB) induced by methamphetamine (METH) and HIV-Tat protein increases the risk of HIV-associated neurocognitive disorders (HAND) in HIV-positive METH abusers.
Jian Huang   +19 more
doaj   +1 more source

Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development

open access: yesPharmacological Reviews, 2020
Compulsive drug seeking that is associated with addiction is hypothesized to follow a heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation) and three domains of dysfunction ...
G. Koob
semanticscholar   +1 more source

Brain networks underlying vulnerability and resilience to drug addiction

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Resting-state functional connectivity provides novel insight into variations in neural networks associated with addiction to stimulant drugs in individuals with and without a family history of addiction, and both with and without personal ...
K. Ersche   +6 more
semanticscholar   +1 more source

Dynamic immune and exosome transcriptomic responses in patients undergoing psychostimulant methamphetamine withdrawal

open access: yesFrontiers in Cellular Neuroscience, 2022
Methamphetamine (METH) addiction and withdrawal cause serious harm to both the immune system and nervous system. However, the pathogenesis remains largely unknown.
Hongjin Wu   +13 more
doaj   +1 more source

Gray-matter structure in long-term abstinent methamphetamine users

open access: yesBMC Psychiatry, 2020
Background Previous studies of brain structure in methamphetamine users have yielded inconsistent findings, possibly reflecting small sample size and inconsistencies in duration of methamphetamine abstinence as well as sampling and analyses methods. Here
Lili Nie   +7 more
doaj   +1 more source

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