Results 31 to 40 of about 2,691,356 (356)
Are cocaine-seeking “habits” necessary for the development of addiction-like behavior in rats? [PDF]
, 2018 Drug self-administration models of addiction typically require animals to make the same response (e.g., a lever-press or nose-poke) over and over to procure and take drugs.
Fadanelli, Monica +3 more
core +2 more sources
Frontiers in Neuroscience, 2021 Mitochondria are dynamic organelles that mediate the energetic supply to cells and mitigate oxidative stress through the intricate balance of fission and fusion.
Michael Kalyn, Marc Ekker
doaj +1 more source
Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]
, 2014 BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J +3 more
core +1 more source
Frontiers in Pharmacology, 2016 Objectives: The recommended zolpidem starting dose was lowered in females (5mg vs 10mg) since side effects were more frequent and severe than those of males; the mechanism underlying sex differences in pharmacokinetics (PK) is unknown.
Cody J Peer +13 more
doaj +1 more source
Comparison of MiSeq, MinION, and hybrid genome sequencing for analysis of Campylobacter jejuni
Scientific Reports, 2021 The sequencing, assembly, and analysis of bacterial genomes is central to tracking and characterizing foodborne pathogens. The bulk of bacterial genome sequencing at the US Food and Drug Administration is performed using short-read Illumina MiSeq ...
Jason M. Neal-McKinney +4 more
doaj +1 more source
Deworming delusions? Mass drug administration in East African schools [PDF]
, 2016 Recent debates about deworming school-aged children in East Africa have been described as the ‘Worm Wars’. The stakes are high. Deworming has become one of the top priorities in the fight against infectious diseases.
Allen, Tim, Parker, Melissa
core +1 more source
Development of Drug-Device Combination Products and Generic Substitution in the United States
INNOVATIONS in PharmacyGeneric drug products approved and marketed in the United States include a variety of drug classes and dosage forms along with drug-device combination products (DDCPs).
YoonJung Lee +6 more
doaj +1 more source
Blood Cancer Journal, 2021 Over the past 13 years, there have been advances in characterizing the patient experience in oncology trials, primarily using patient-reported outcomes (PROs). This review aims to provide details on the PRO measures and analyses used in multiple myeloma (
Laura L. Fernandes +6 more
doaj +1 more source
Corticosterone Acts in the Nucleus Accumbens to Enhance Dopamine Signaling and Potentiate Reinstatement of Cocaine Seeking [PDF]
, 2013 Stressful life events are important contributors to relapse in recovering cocaine addicts, but the mechanisms by which they influence motivational systems are poorly understood.
Baker, David A. +10 more
core +2 more sources
Sublingual Administration of Drugs [PDF]
Anesthesiology, 1944 In discussions of therapeutic technics there is frequently recurring opinion to the effect that any of the potent nonirritant drugs may be effectively administered by simple application to the oral mucosa. 1 Very few drugs, however, are routinely used in this way in regular practice.
openaire +3 more sources