Results 121 to 130 of about 415,670 (364)
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Recent advances in smart biotechnology: Hydrogels and nanocarriers for tailored bioactive molecules depot [PDF]
, 2017 Over the past ten years, the global biopharmaceutical market has remarkably grown, with ten over the top twenty worldwide high performance medical treatment sales being biologics.
Antunes, Filipe E. +12 more
core +2 more sources
Role of surface heterogeneous nucleation on nanoporous drug delivery systems [PDF]
arXiv, 2019 In this work we investigate the use of nanoporous carrier as drug delivery systems for hydrophobic molecules. By studying a model system made of porous silicon loaded with beta-carotene, we unveil a fundamental limitation of these carriers that is due to heterogeneous nucleation that imposes a tradeoff between the amount of drug loaded and the ...
arxiv
Efficient integration and fast excretion of drug carrier: The trojan horse for cancer therapy
Smart Materials in Medicine, 2020 Macromolecular engineering has benefited the fabrication of drug delivery systems, owing to the versatile and tunable physical and chemical properties of the polymeric carriers as needed. However, the slow excretion rate of the macromolecule carriers has
Wang Zhen, Wenguo Cui
doaj
Siderophore: A Suitable Candidate for Drug Delivery Using the Trojan Horse Strategy
Medical Laboratory Journal, 2021 Increasing antibiotic resistance is a global health problem. In recent years, due to the indiscriminate use of antibacterial compounds, many bacterial pathogens, including staphylococci, members of the Enterobacteriaceae family including Klebsiella ...
Behnoush Khasheii +2 more
doaj
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]
, 2009 The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M. +1 more
core +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Mucosal delivery of liposome-chitosan nanoparticles complexes [PDF]
, 2009 Designing adequate drug carriers has long been a major challenge for those working in drug delivery. Since drug delivery strategies have evolved for mucosal delivery as the outstanding alternative to parenteral administration, many new drug delivery ...
Alonso, Maria José +4 more
core
Smart systems related to polypeptide sequences [PDF]
, 2016 Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence.
Franco García, María Lourdes +2 more
core +2 more sources