Results 171 to 180 of about 212,322 (308)

Functionalization of carbon nanospheres with curcumin, polyethylene glycol and folic acid: potential use as drug carriers. [PDF]

RSC Adv
De Sales L, Bernal-Chávez SA, Campos-Delgado J.   +2 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Intratumoral vascular damage-dependent drug permeability and anticancer effect of nano drug carriers: significant anticancer enhancement of combination therapy. [PDF]

J Nanobiotechnology
Moon D, Kim D, Balwe SG, Song JM.
europepmc   +1 more source

Chitosan Nanoparticles as Oral Drug Carriers. [PDF]

Int J Mol Sci, 2023
Guadarrama-Escobar OR, Serrano-Castañeda P, Anguiano-Almazán E, Vázquez-Durán A, Peña-Juárez MC, Vera-Graziano R, Morales-Florido MI, Rodriguez-Perez B, Rodriguez-Cruz IM, Miranda-Calderón JE, Escobar-Chávez JJ.   +10 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fiber-Based Scaffolds as Drug Carriers: Recent Advances. [PDF]

Pharmaceutics
Felgueiras HP.
europepmc   +1 more source

Biomimetic Collagen Membranes as Drug Carriers of Geranylgeraniol to Counteract the Effect of Zoledronate. [PDF]

Biomimetics (Basel), 2023
Manzano-Moreno FJ, de Luna-Bertos E, Toledano-Osorio M, Urbano-Arroyo P, Ruiz C, Toledano M, Osorio R.   +6 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Editorial: Driving extracellular vesicles toward applications in precision medicine

Frontiers in Medicine, 2022
Somchai Chutipongtanate, Somchai Chutipongtanate, Somchai Chutipongtanate, Somchai Chutipongtanate, Kovit Pattanapanyasat, Jarek Meller, Jarek Meller, Jarek Meller, Juana Serrano López   +8 more
doaj   +1 more source

Prospects and Challenges of Chitosan-Based Drug Carriers for Anticancer Agents' Delivery Against Lung Cancer: A Review. [PDF]

Drug Des Devel Ther
Liu Y, Yang B, Chen H, Liao Y, Zhang S, Yang J, Chen W, Liu H.   +7 more
europepmc   +1 more source