Results 191 to 200 of about 211,400 (307)

Advances in Self-Assembled Peptides as Drug Carriers. [PDF]

Pharmaceutics, 2023
Gao Y, Wang L, Zhang X, Zhou Z, Shen X, Hu H, Sun R, Tang J.   +7 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration. [PDF]

ChemistryOpen
Nining N, Wardhana YW, Rusdiana T, Hariyanti H.   +3 more
europepmc   +1 more source

Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers. [PDF]

Int J Mol Sci, 2023
Tsuchiya K, Horikoshi K, Fujita M, Hirano M, Miyamoto M, Yokoo H, Demizu Y.   +6 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Nanoparticulates as drug carriers

, 2006
Torchilin, V. P.
core  

Probiotic Bacteria as Therapeutics and Biohybrid Drug Carriers: Advances, Design Strategies, and Future Outlook. [PDF]

ACS Appl Bio Mater
Sahoo D, Rodriguez E, Nguyen K, Chintapula U.   +3 more
europepmc   +1 more source

Lipoproteins as Drug Carriers for Cyclosporine A: Optimization of the Entrapment. [PDF]

Materials (Basel), 2023
Abdel-Mottaleb MMA, Boi L, Barra M, Colin J, Berni L, Béduneau A, Moulari B, Pellequer Y.   +7 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Hydrogels as a new platform of therapeutic systems in oncological treatment - use as a protective barrier and drug carriers. [PDF]

Front Bioeng Biotechnol
Czerwiec K, Szczecińska W, Pikuła M.
europepmc   +1 more source