Synthesis and Characterization of Water-Soluble EDTA-Crosslinked Poly-β-Cyclodextrins Serving as Ion-Complexing Drug Carriers. [PDF]
Podgórniak Z +5 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Nanogels-Innovative Drug Carriers for Overcoming Biological Membranes. [PDF]
Radeva L, Yoncheva K.
europepmc +1 more source
Advances in Self-Assembled Peptides as Drug Carriers. [PDF]
Gao Y +7 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration. [PDF]
Nining N +3 more
europepmc +1 more source
Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers. [PDF]
Tsuchiya K +6 more
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Probiotic Bacteria as Therapeutics and Biohybrid Drug Carriers: Advances, Design Strategies, and Future Outlook. [PDF]
Sahoo D +3 more
europepmc +1 more source
Lipoproteins as Drug Carriers for Cyclosporine A: Optimization of the Entrapment. [PDF]
Abdel-Mottaleb MMA +7 more
europepmc +1 more source

