Results 181 to 190 of about 422,254 (308)

Exosomes: potential diagnostic markers and drug carriers for adenomyosis. [PDF]

Front Pharmacol, 2023
Cheng WX, Wei SB, Zhou Y, Shao Y, Li MY.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Functionalized Halloysite Nanotubes as Potential Drug Carriers. [PDF]

J Funct Biomater, 2023
Stodolak-Zych E, Rapacz-Kmita A, Gajek M, Różycka A, Dudek M, Kluska S.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration. [PDF]

ChemistryOpen
Nining N, Wardhana YW, Rusdiana T, Hariyanti H.   +3 more
europepmc   +1 more source

Advances in Self-Assembled Peptides as Drug Carriers. [PDF]

Pharmaceutics, 2023
Gao Y, Wang L, Zhang X, Zhou Z, Shen X, Hu H, Sun R, Tang J.   +7 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Nanogels-Innovative Drug Carriers for Overcoming Biological Membranes. [PDF]

Gels
Radeva L, Yoncheva K.
europepmc   +1 more source

Development of Hydrophobic Cell-Penetrating Stapled Peptides as Drug Carriers. [PDF]

Int J Mol Sci, 2023
Tsuchiya K, Horikoshi K, Fujita M, Hirano M, Miyamoto M, Yokoo H, Demizu Y.   +6 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source