Results 261 to 270 of about 211,400 (307)
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Carrier Deformability in Drug Delivery
Current Pharmaceutical Design, 2016Deformability is a key property of drug carriers used to increase the mass penetration across the skin without disrupting the lipid barrier. Highly deformable vesicles proved to be more effective than conventional liposomes in delivering drugs into and across the mammalian skin upon topical non occlusive application.
Morilla, María José +1 more
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Polymeric microspheres as drug carriers
Biomaterials, 1988The use of polymeric microsphere systems (including polypeptides) as vehicles for delivering drugs by a variety of routes is considered with particular reference to parenteral administration. Microsphere formulation is discussed with emphasis on the role of surface properties and how these can determine the fate of administered particles.
S S, Davis, L, Illum
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Driving forces for drug loading in drug carriers
Journal of Microencapsulation, 2015The loading capacity of a drug carrier is determined essentially by intermolecular interactions between drugs and carrier materials. In this review, the process of drug loading is described in detail based on the differences in the driving force for drug incorporation, including hydrophobic interaction, electrostatic interaction, hydrogen bonding, Pi ...
Yang, Li, Li, Yang
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Engineering in Medicine, 1986
Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Site-specific drug carriers are required to exclusively deliver drug molecules to difficult targets within the body. They should do so in a form which protects the drug and host from one another. This contribution reviews the reasons for drug targeting, and describes some of the features required of two types of carrier system, i.e., particulates and ...
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Molecular Pharmaceutics, 2018
We have performed two sets of all atom molecular dynamics (MD) simulations of poly(acrylic acid) (PAA) oligomers, considered as a model pH-responsive drug carrier. In the first set, multiple oligomers of PAA are simulated in model gastric and intestinal fluids, where the degree of deprotonation of PAA oligomers is varied with the medium pH.
Ratna S. Katiyar, Prateek K. Jha
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We have performed two sets of all atom molecular dynamics (MD) simulations of poly(acrylic acid) (PAA) oligomers, considered as a model pH-responsive drug carrier. In the first set, multiple oligomers of PAA are simulated in model gastric and intestinal fluids, where the degree of deprotonation of PAA oligomers is varied with the medium pH.
Ratna S. Katiyar, Prateek K. Jha
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Peptide vectors as drug carriers
2003During the last decade, several peptides have been described, such as SynB vectors [1] penetratin and Tat [2, 3] that allow the intracellular delivery of polar, biologically active compounds in vitro and in vivo [2, 4]. These peptides, belonging to various families, are heterogeneous in size (10 to 18 amino acids) and sequence (Tab. 1).
Jamal, Temsamani +1 more
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Albumin-Based Nanodevices as Drug Carriers
Current Pharmaceutical Design, 2016Nanomedicine, the application of nanotechnology to medicine, is being increasingly used to improve and exploit the advantages of efficient drug delivery. Different nanodevices have been developed in recent years, among them protein-based nanoparticles which have gained considerable interest.
Loureiro, Ana Isabel Sá +3 more
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Lipid Formulation as a Drug Carrier for Drug Delivery
Current Pharmaceutical Design, 2002In recent years, a Drug Delivery System (DDS), a preparative approach attracts the attention in the development of new drugs. DDS focuses on the regulation of the in vivo dynamics, such as absorption, distribution, metabolism, and elimination, thereby improving the effectiveness and the safety of the drugs by an applicable use of drug preparation ...
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Asian Journal of Research in Pharmaceutical Science, 2019
One of various talented new drug delivery systems, liposomes characterize an advanced technology to deliver active molecules to the site of action, and at present, several formulations are in clinical use. The liposome consist of phospholipids, which have phosphoric acid sides to form the liposome players.
Tabasum Siraj Mulla +3 more
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One of various talented new drug delivery systems, liposomes characterize an advanced technology to deliver active molecules to the site of action, and at present, several formulations are in clinical use. The liposome consist of phospholipids, which have phosphoric acid sides to form the liposome players.
Tabasum Siraj Mulla +3 more
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Drug targeting by drug entrapment into ultrafine compartments as carriers
Applied Biochemistry and Biotechnology, 1984The incorporation of drugs into vesicles is one of several technological methods for the optimization of targeted drug delivery and controlled drug targeting. The main problems will always remain: To design inert auxiliary accompanying materials in order to overcome side reactions; To use body-friendly and biodegradable macromolecular carrier materials
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