Results 61 to 70 of about 4,747,249 (340)
Molecules, 2020 Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as potential drug delivery systems for various applications that are produced from physiological, biodegradable, and biocompatible lipids.
Van-An Duong +2 more
semanticscholar +1 more source
Spotlight on Biomimetic Systems Based on Lyotropic Liquid Crystal
Molecules, 2017 The behavior of lyotropic biomimetic systems in drug delivery was reviewed. These behaviors are influenced by drug properties, the initial water content, type of lyotropic liquid crystals (LLC), swell ability, drug loading rate, the presence of ions with
Juliana F. de Souza +6 more
doaj +1 more source
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Micro- and nano-motors: the new generation of drug carriers.
Therapeutic delivery, 2018 Micro- and nano-motors are emerging as novel drug delivery platforms, offering advantages such as rapid drug transport, high tissue penetration and motion controllability.
M. Medina‐Sánchez +2 more
semanticscholar +1 more source
Cells and cell derivatives as drug carriers for targeted delivery
Medicine in Drug Discovery, 2019 For over a century, researchers have focused on how to optimize drug delivery. Systemic administration means that the drug becomes dilute and has the potential to diffuse to all tissues, which is only until the immune system steps in and rapidly clears ...
Halle Lutz +3 more
doaj
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Biomedical Applications of Nano-Sized Polymeric Micelles and Polyion Complexes [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2018 The paper provides a high-level overview of the use of polymeric micelles, polyion complexes, cell mediated drug carriers and exosomes in the therapy of cancer and neurodegenerative diseases.
Alexander Kabanov
doaj
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
New insights into the degradation mechanism of metal-organic frameworks drug carriers
Scientific Reports, 2017 A versatile method based on Raman microscopy was developed to follow the degradation of iron carboxylate Metal Organic Framework (MOF) nano- or micro-particles in simulated body fluid (phosphate buffer).
Xia Li +7 more
semanticscholar +1 more source