Results 71 to 80 of about 415,670 (364)

Handgun carrying among youth in the United States [PDF]

open access: yes, 2016
Despite a wealth of research finding that adolescents who carry handguns are involved in risky behaviors, there has been little exploration into the heterogeneity of this behavior.
Boutwell, Brian B.   +4 more
core   +1 more source

Charge-reversal nanoparticles: novel targeted drug delivery carriers

open access: yesActa Pharmaceutica Sinica B, 2016
Spurred by significant progress in materials chemistry and drug delivery, charge-reversal nanocarriers are being developed to deliver anticancer formulations in spatial-, temporal- and dosage-controlled approaches.
Xinli Chen, Lisha Liu, Chen Jiang
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Molecular modeling to study dendrimers for biomedical applications [PDF]

open access: yes, 2014
© 2014 by the authors; licensee MDPI; Basel; Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
Buhleier   +15 more
core   +3 more sources

Biochemically altered human erythrocytes as a carrier for targeted delivery of primaquine: an in vitro study [PDF]

open access: yesArch. Pharm. Res. (2011) 34: 563, 2019
The aim of this study was to investigate human erythrocytes as a carrier for targeted drug delivery of primaquine (PQ). The process of PQ loading in human erythrocytes, as well as the effect of PQ loading on the oxidative status of erythrocytes, was also studied.
arxiv   +1 more source

Cells and cell derivatives as drug carriers for targeted delivery

open access: yesMedicine in Drug Discovery, 2019
For over a century, researchers have focused on how to optimize drug delivery. Systemic administration means that the drug becomes dilute and has the potential to diffuse to all tissues, which is only until the immune system steps in and rapidly clears ...
Halle Lutz   +3 more
doaj  

Ciprofloxacin-Loaded Mixed Polymeric Micelles as Antibiofilm Agents

open access: yesPharmaceutics, 2023
In this work, mixed polymeric micelles (MPMs) based on a cationic poly(2-(dimethylamino)ethyl methacrylate)-b-poly(ε-caprolactone)-b-poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA29-b-PCL70-b-PDMAEMA29) and a non-ionic poly(ethylene oxide)–b-poly ...
Rumena Stancheva   +5 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

A novel Malonamide Periodic Mesoporous Organosilica (PMO) for controlled Ibuprofen release [PDF]

open access: yes, 2015
Controlled drug release gained a sharply increasing interest over recent years. Multiple materials have been screened as possible drug carriers, ranging from biodegradable polymers to hydroxyapatite[1].
Clerick, Sander   +5 more
core  

Evaluation of the Role of Different Bottom-Up Synthesis Procedures for Carbon Dots in Their Potential as Candidates as Drug Carriers

open access: yesMedical Sciences Forum, 2022
Carbon Dots (CDs) application in biomedicine has been increasing, due to their properties of high photoluminescence, biosafety and low cost, which allow for possible applications in bioimaging and as drug carriers. However, their synthesis strategies are
Diana Crista   +2 more
doaj   +1 more source

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