Results 11 to 20 of about 769,426 (246)
Candyflipping and Other Combinations: Identifying Drug–Drug Combinations from an Online Forum [PDF]
Frontiers in Psychiatry, 2018 Novel psychoactive substances (NPS) refer to synthetic compounds or derivatives of more widely known substances of abuse that have emerged over the last two decades.
Michael Chary, David Yi, Alex F. Manini
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Drug interactions and lethal drug combinations [PDF]
Journal of Clinical Pathology, 1975 A. Richens
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Molecules, 2021 Despite Alzheimer’s disease (AD) incidence being projected to increase worldwide, the drugs currently on the market can only mitigate symptoms. Considering the failures of the classical paradigm “one target-one drug-one disease” in delivering effective ...
Claudia Albertini +7 more
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Corrigendum: Network-based prediction of anti-cancer drug combinations [PDF]
Frontiers in PharmacologyJue Jiang +4 more
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Understanding the Clinical Use of Levosimendan and Perspectives on its Future in Oncology
Biomolecules, 2023 Drug repurposing, also known as repositioning or reprofiling, has emerged as a promising strategy to accelerate drug discovery and development. This approach involves identifying new medical indications for existing approved drugs, harnessing the ...
Eduarda Ribeiro, Nuno Vale
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Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug [PDF]
, 2013 BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Adelfio, R. +5 more
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Search algorithms as a framework for the optimization of drug combinations [PDF]
, 2008 Combination therapies are often needed for effective clinical outcomes in the management of complex diseases, but presently they are generally based on empirical clinical experience.
A Wagner +44 more
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Pharmaceutics, 2022 The fast evolution of anti-tumor agents embodies a deeper understanding of cancer pathogenesis. To date, chemotherapy, targeted therapy, and immunotherapy are three pillars of the paradigm for cancer treatment. The success of immune checkpoint inhibitors
Tiancheng Zhang +3 more
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Bifunctional antibiotic hybrids: A review of clinical candidates
Frontiers in Pharmacology, 2023 Antibiotic resistance is a top threat to human health and a priority across the globe. This problematic issue is accompanied by the decline of new antibiotics in the pipeline over the past 30 years.
Augustine Jing Jie Koh +6 more
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