Results 81 to 90 of about 4,579,977 (389)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]

open access: yes, 2016
Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core   +2 more sources

Occurrence of bacterial and toxic metals contamination in illegal opioid-like drugs in Iran: a significant health challenge in drug abusers

open access: yesDARU Journal of Pharmaceutical Sciences, 2018
The toxic metals and/or bacterial contaminants in illicit drugs are the main health problems in drug users worldwide. Hence, the potential risks of these contaminants were evaluated in some of the illicit drugs during 2015 and 2016.
Rassoul Aghababaei   +4 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Study on contamination and drug resistance of important foodborne pathogens in fresh cut fruits and vegetables retailed in five districts of Beijing

open access: yesZhongguo shipin weisheng zazhi, 2021
ObjectiveIn order to explore the contamination and drug resistance of foodborne pathogens in fresh cut fruits and vegetables, samples were collected from retail markets in five district in Beijing.MethodsThe national standard method of food ...
BAI Yao   +10 more
doaj   +1 more source

Potential of Mobile Phones to Serve as a Reservoir in Spread of Nosocomial Pathogens [PDF]

open access: yes, 2011
Objective: The use of cellular telephones by medical personnel and the associated nosocomial transmission of pathogens have not been thoroughly examined.
Bhat, SS, Hegde, SK, Salian, S
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Impact of a Probiotic-Based Cleaning Intervention on the Microbiota Ecosystem of the Hospital Surfaces: Focus on the Resistome Remodulation. [PDF]

open access: yesPLoS ONE, 2016
Contamination of hospital surfaces by clinically-relevant pathogens represents a major concern in healthcare facilities, due to its impact on transmission of healthcare-associated infections (HAIs) and to the growing drug resistance of HAI-associated ...
Elisabetta Caselli   +10 more
doaj   +1 more source

Compounding drugs contaminated with fungi: a recipe for disaster

open access: yesEmerging Microbes & Infections, 2012
Emerging Microbes & Infections (2012) 1, e41; doi:10.1038/emi.2012.46 An ongoing outbreak of fungal meningitis in the United States has been traced to injections of contaminated corticosteroids produced by a compounding pharmacy.
openaire   +4 more sources

Environmental Contamination with Hazardous Drugs in Quebec Hospitals

open access: yesThe Canadian Journal of Hospital Pharmacy, 2012
Since publication of the US National Institute for Occupational Safety and Health alert on hazardous drugs in 2004, many health care organizations have reviewed their procedures for handling hazardous drugs. Occupational exposure may occur when handling, compounding, or administering a drug considered to be hazardous, at any stage from storage to waste
Michel Lefebvre   +4 more
openaire   +4 more sources

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