Results 1 to 10 of about 754,926 (313)

3D Printed Hollow Microneedles for Treating Skin Wrinkles Using Different Anti-Wrinkle Agents: A Possible Futuristic Approach

Cosmetics, 2023
Skin wrinkles are an inevitable phenomenon that is brought about by aging due to the degradation of scleroprotein fibers and significant collagen reduction, which is the fundamental basis of anti-wrinkle technology in use today.
Humayra Islam, Taslima Sultana Poly, Zarin Tasnim Tisha, Samia Rahman, Ahmed Issa Jahangir Naveed, Alifa Ahmed, Saraf Nawar Ahmed, Jasmin Hassan, Md. Jasim Uddin, Diganta B. Das   +9 more
doaj   +1 more source

Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Pharmaceutics, 2022
Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment.
Mathilde Bausart, Kevin Vanvarenberg, Bernard Ucakar, Alessandra Lopes, Gaëlle Vandermeulen, Alessio Malfanti, Véronique Préat   +6 more
doaj   +1 more source

Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics

Journal of Nanotechnology, 2022
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale, Olakunle Oladimeji, Mario Ariatti, Moganavelli Singh   +3 more
doaj   +1 more source

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

Drug Delivery, 2021
Although prednisolone (PD) is used as an anti-arthritis drug due to its rapid and strong anti-inflammatory potential, its frequent and large dosing often brings about adverse effects.
Kohei Mizuno, Yuri Ikeuchi-Takahashi, Yoshiyuki Hattori, Hiraku Onishi   +3 more
doaj   +1 more source

Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma

Pharmaceutics, 2022
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the glioblastoma site, and consequently reducing systemic toxicity.
Alessio Malfanti, Giuseppina Catania, Quentin Degros, Mingchao Wang, Mathilde Bausart, Véronique Préat   +5 more
doaj   +1 more source

Drug delivery

Nature Biotechnology, 2023
The speed of the various physiological processes that affect wound healing depends on therapeutic agents, such as cytokines, antibacterial agents, growth factors, small molecules, proteins and bioactive agents. In addition to the speed of healing, there are several factors that should be considered in deciding the route of administration of therapies ...
Delleani S., Lacroce E., Rossi F.
openaire   +4 more sources

Immunotherapy for glioblastoma: the promise of combination strategies

Journal of Experimental & Clinical Cancer Research, 2022
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy.
Mathilde Bausart, Véronique Préat, Alessio Malfanti   +2 more
doaj   +1 more source

Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury

Asian Journal of Pharmaceutical Sciences, 2023
Acute liver injury (ALI) has an elevated fatality rate due to untimely and ineffective treatment. Although, schisandrin B (SchB) has been extensively used to treat diverse liver diseases, its therapeutic efficacy on ALI was limited due to its high ...
Rongping Zhang, Shiqing Luo, Ting Zhao, Mengying Wu, Lu Huang, Ling Zhang, Yuan Huang, Huile Gao, Xun Sun, Tao Gong, Zhirong Zhang   +10 more
doaj   +1 more source

Sustainable Aquafeed Formulations Containing Insect Larval Meal and Grape Marc for the New Zealand Farmed Abalone

Aquaculture Nutrition, 2023
The aquaculture industry has been criticised for the excessive use of fish meal (FM) in feeds due to the utilisation of wild fish in the formulation and the exacerbation of overfishing marine resources.
Natalia Bullon, Andrea C. Alfaro, Moganakumaar Manivannan, Seyedehsara Masoomi Dezfooli, Ali Seyfoddin   +4 more
doaj   +1 more source

Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor‐associated macrophages

Acta Pharmaceutica Sinica B, 2023
As known, the benefits of photothermal therapy (PTT) are greatly limited by the heat tolerance of cancer cells resulting from overexpressed heat shock proteins (HSPs). Then HSPs further trigger the formation of stress granules (SGs) that regulate protein
Fan Tong, Haili Hu, Yanyan Xu, Yang Zhou, Rou Xie, Ting Lei, Yufan Du, Wenqin Yang, Siqin He, Yuan Huang, Tao Gong, Huile Gao   +11 more
doaj   +1 more source