Results 1 to 10 of about 700,446 (274)

3D Printed Hollow Microneedles for Treating Skin Wrinkles Using Different Anti-Wrinkle Agents: A Possible Futuristic Approach

Cosmetics, 2023
Skin wrinkles are an inevitable phenomenon that is brought about by aging due to the degradation of scleroprotein fibers and significant collagen reduction, which is the fundamental basis of anti-wrinkle technology in use today.
Humayra Islam, Taslima Sultana Poly, Zarin Tasnim Tisha, Samia Rahman, Ahmed Issa Jahangir Naveed, Alifa Ahmed, Saraf Nawar Ahmed, Jasmin Hassan, Md. Jasim Uddin, Diganta B. Das   +9 more
doaj   +1 more source

Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Pharmaceutics, 2022
Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment.
Mathilde Bausart, Kevin Vanvarenberg, Bernard Ucakar, Alessandra Lopes, Gaëlle Vandermeulen, Alessio Malfanti, Véronique Préat   +6 more
doaj   +1 more source

Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics

Journal of Nanotechnology, 2022
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale, Olakunle Oladimeji, Mario Ariatti, Moganavelli Singh   +3 more
doaj   +1 more source

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

Drug Delivery, 2021
Although prednisolone (PD) is used as an anti-arthritis drug due to its rapid and strong anti-inflammatory potential, its frequent and large dosing often brings about adverse effects.
Kohei Mizuno, Yuri Ikeuchi-Takahashi, Yoshiyuki Hattori, Hiraku Onishi   +3 more
doaj   +1 more source

Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma

Pharmaceutics, 2022
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the glioblastoma site, and consequently reducing systemic toxicity.
Alessio Malfanti, Giuseppina Catania, Quentin Degros, Mingchao Wang, Mathilde Bausart, Véronique Préat   +5 more
doaj   +1 more source

Immunotherapy for glioblastoma: the promise of combination strategies

Journal of Experimental & Clinical Cancer Research, 2022
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy.
Mathilde Bausart, Véronique Préat, Alessio Malfanti   +2 more
doaj   +1 more source

Sustainable Aquafeed Formulations Containing Insect Larval Meal and Grape Marc for the New Zealand Farmed Abalone

Aquaculture Nutrition, 2023
The aquaculture industry has been criticised for the excessive use of fish meal (FM) in feeds due to the utilisation of wild fish in the formulation and the exacerbation of overfishing marine resources.
Natalia Bullon, Andrea C. Alfaro, Moganakumaar Manivannan, Seyedehsara Masoomi Dezfooli, Ali Seyfoddin   +4 more
doaj   +1 more source

Efficacy of Intra-Articular Injection of Botulinum Toxin Type A (IncobotulinumtoxinA) in Temporomandibular Joint Osteoarthritis: A Three-Arm Controlled Trial in Rats

Toxins, 2023
Temporomandibular disorders (TMD) are complex pathologies responsible for chronic orofacial pain. Intramuscular injection of botulinum toxin A (BoNT/A) has shown effectiveness in knee and shoulder osteoarthritis, as well as in some TMDs such as ...
Marie Béret, Florent Barry, Maria-Jose Garcia-Fernandez, Henry Chijcheapaza-Flores, Nicolas Blanchemain, Feng Chai, Romain Nicot   +6 more
doaj   +1 more source

Mathematical modeling of shear-activated targeted nanoparticle drug delivery for the treatment of aortic diseases [PDF]

Biomechanics and Modeling in Mechanobiology (2021), 2021
The human aorta is a high-risk area for vascular diseases, which are commonly restored by thoracic endovascular aortic repair. In this paper, we report a promising shear-activated targeted nanoparticle drug delivery strategy to assist in the treatment of coarctation of the aorta and aortic aneurysm.
arxiv   +1 more source

Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel

Pharmaceutics, 2022
The management of retinoblastoma (RB) involves the use of invasive treatment regimens. Paclitaxel (PTX), an effective antineoplastic compound used in the treatment of a wide range of malignant tumors, poses treatment challenges due to systemic toxicity ...
Sushrut Marathe, Gauri Shadambikar, Tabish Mehraj, Suresh P. Sulochana, Narendar Dudhipala, Soumyajit Majumdar   +5 more
doaj   +1 more source