Results 1 to 10 of about 717,648 (284)

3D Printed Hollow Microneedles for Treating Skin Wrinkles Using Different Anti-Wrinkle Agents: A Possible Futuristic Approach

open access: yesCosmetics, 2023
Skin wrinkles are an inevitable phenomenon that is brought about by aging due to the degradation of scleroprotein fibers and significant collagen reduction, which is the fundamental basis of anti-wrinkle technology in use today.
Humayra Islam   +9 more
doaj   +1 more source

Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

open access: yesPharmaceutics, 2022
Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment.
Mathilde Bausart   +6 more
doaj   +1 more source

Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics

open access: yesJournal of Nanotechnology, 2022
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale   +3 more
doaj   +1 more source

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

open access: yesDrug Delivery, 2021
Although prednisolone (PD) is used as an anti-arthritis drug due to its rapid and strong anti-inflammatory potential, its frequent and large dosing often brings about adverse effects.
Kohei Mizuno   +3 more
doaj   +1 more source

Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma

open access: yesPharmaceutics, 2022
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the glioblastoma site, and consequently reducing systemic toxicity.
Alessio Malfanti   +5 more
doaj   +1 more source

Immunotherapy for glioblastoma: the promise of combination strategies

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy.
Mathilde Bausart   +2 more
doaj   +1 more source

Drug delivery

open access: yesNature Biotechnology, 2023
The speed of the various physiological processes that affect wound healing depends on therapeutic agents, such as cytokines, antibacterial agents, growth factors, small molecules, proteins and bioactive agents. In addition to the speed of healing, there are several factors that should be considered in deciding the route of administration of therapies ...
Delleani S., Lacroce E., Rossi F.
openaire   +4 more sources

Sustainable Aquafeed Formulations Containing Insect Larval Meal and Grape Marc for the New Zealand Farmed Abalone

open access: yesAquaculture Nutrition, 2023
The aquaculture industry has been criticised for the excessive use of fish meal (FM) in feeds due to the utilisation of wild fish in the formulation and the exacerbation of overfishing marine resources.
Natalia Bullon   +4 more
doaj   +1 more source

Efficacy of Intra-Articular Injection of Botulinum Toxin Type A (IncobotulinumtoxinA) in Temporomandibular Joint Osteoarthritis: A Three-Arm Controlled Trial in Rats

open access: yesToxins, 2023
Temporomandibular disorders (TMD) are complex pathologies responsible for chronic orofacial pain. Intramuscular injection of botulinum toxin A (BoNT/A) has shown effectiveness in knee and shoulder osteoarthritis, as well as in some TMDs such as ...
Marie Béret   +6 more
doaj   +1 more source

Stomaching Drug Delivery [PDF]

open access: yesNew England Journal of Medicine, 2019
The Tortoise and the Tummy The gastric mucosa represents a formidable barrier to oral drug delivery.
David J. Brayden, Alan W. Baird
openaire   +5 more sources

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