Results 11 to 20 of about 6,495,283 (386)

3D Printed Hollow Microneedles for Treating Skin Wrinkles Using Different Anti-Wrinkle Agents: A Possible Futuristic Approach

open access: yesCosmetics, 2023
Skin wrinkles are an inevitable phenomenon that is brought about by aging due to the degradation of scleroprotein fibers and significant collagen reduction, which is the fundamental basis of anti-wrinkle technology in use today.
Humayra Islam   +9 more
doaj   +1 more source

Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

open access: yesPharmaceutics, 2022
Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment.
Mathilde Bausart   +6 more
doaj   +1 more source

The blood–brain barrier: Structure, regulation and drug delivery

open access: yesSignal Transduction and Targeted Therapy, 2023
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However, the presence of BBB complicates the pharmacotherapy for CNS disorders as the most chemical drugs and ...
Di Wu   +5 more
semanticscholar   +1 more source

Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics

open access: yesJournal of Nanotechnology, 2022
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale   +3 more
doaj   +1 more source

Polymer-Based Hydrogels Applied in Drug Delivery: An Overview

open access: yesGels, 2023
Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied for drug delivery applications because of their ability to hold large amounts of water and biological fluids and control drug release based on their unique ...
N. Thang, Truong Bach Chien, D. Cuong
semanticscholar   +1 more source

Preparation and evaluation of conjugate nanogels of glycyl-prednisolone with natural anionic polysaccharides as anti-arthritic delivery systems

open access: yesDrug Delivery, 2021
Although prednisolone (PD) is used as an anti-arthritis drug due to its rapid and strong anti-inflammatory potential, its frequent and large dosing often brings about adverse effects.
Kohei Mizuno   +3 more
doaj   +1 more source

Design of Bio-Responsive Hyaluronic Acid–Doxorubicin Conjugates for the Local Treatment of Glioblastoma

open access: yesPharmaceutics, 2022
Glioblastoma is an unmet clinical need. Local treatment strategies offer advantages, such as the possibility to bypass the blood–brain barrier, achieving high drug concentrations at the glioblastoma site, and consequently reducing systemic toxicity.
Alessio Malfanti   +5 more
doaj   +1 more source

Immunotherapy for glioblastoma: the promise of combination strategies

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy.
Mathilde Bausart   +2 more
doaj   +1 more source

Engineering precision nanoparticles for drug delivery

open access: yesNature reviews. Drug discovery, 2020
In recent years, the development of nanoparticles has expanded into a broad range of clinical applications. Nanoparticles have been developed to overcome the limitations of free therapeutics and navigate biological barriers — systemic, microenvironmental
M. J. Mitchell   +5 more
semanticscholar   +1 more source

Sustainable Aquafeed Formulations Containing Insect Larval Meal and Grape Marc for the New Zealand Farmed Abalone

open access: yesAquaculture Nutrition, 2023
The aquaculture industry has been criticised for the excessive use of fish meal (FM) in feeds due to the utilisation of wild fish in the formulation and the exacerbation of overfishing marine resources.
Natalia Bullon   +4 more
doaj   +1 more source

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