Results 11 to 20 of about 717,648 (284)

Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel

open access: yesPharmaceutics, 2022
The management of retinoblastoma (RB) involves the use of invasive treatment regimens. Paclitaxel (PTX), an effective antineoplastic compound used in the treatment of a wide range of malignant tumors, poses treatment challenges due to systemic toxicity ...
Sushrut Marathe   +5 more
doaj   +1 more source

Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery

open access: yesScientific Reports, 2021
Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment.
Yong Yao Chun   +8 more
doaj   +1 more source

Microfabrication for Drug Delivery [PDF]

open access: yesMaterials, 2016
This review is devoted to discussing the application of microfabrication technologies to target challenges encountered in life processes by the development of drug delivery systems. Recently, microfabrication has been largely applied to solve health and pharmaceutical science issues.
Brendan Koch   +4 more
openaire   +3 more sources

Translation of ionic liquids to be enteric nanoparticles for facilitating oral absorption of cyclosporine A

open access: yesBioengineering & Translational Medicine, 2023
Ionic liquids (ILs) attract more and more interests in improving drug transport across membrane, including transdermal, nasal, and oral delivery. However, some drawbacks of ILs impede the application in oral drug delivery, such as rapid precipitation of ...
Kaiheng Liu   +9 more
doaj   +1 more source

New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus ...
Alessandra Lopes   +8 more
doaj   +1 more source

A Promising Drug Delivery: Intranasal Drug Delivery System

open access: yesInternational Journal of Pharmaceutical Sciences Review and Research, 2021
Pneumonic medication conveyance has acquired gigantic logical interest as of late and has advanced inside the setting of treatment for lung infections. Lung is an appealing climate for bio particles, which are exceptionally presented to enzymatic debasement in the gastrointestinal parcel just as hepatic corruption.
M. Srinivas, Y. Kalyani, J. V. C. Sharma
openaire   +2 more sources

Nanofibres in Drug Delivery [PDF]

open access: yes, 2018
In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, and to explain to them how to prepare fibres in the laboratory.
Williams, GH, Raimi-Abraham, BT, Luo, C
openaire   +5 more sources

Dendrimers for Drug Delivery [PDF]

open access: yesMolecules, 2018
Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr. Donald Tomalia first published his seminal work on Poly(amidoamine) (PAMAM) dendrimers in 1985. Application of dendrimers as a drug delivery system started in late 1990s.
openaire   +4 more sources

Photoacoustic Drug Delivery

open access: yesSensors, 2017
Photoacoustic (PA) technology holds great potential in clinical translation as a new non-invasive bioimaging modality. In contrast to conventional optical imaging, PA imaging (PAI) enables higher resolution imaging with deeper imaging depth. Besides applications for diagnosis, PA has also been extended to theranostic applications.
Zhen Gu   +3 more
openaire   +3 more sources

Nanoencapsulation for drug delivery [PDF]

open access: yesEXCLI journal, 2014
Nanoencapsulation of drug/small molecules in nanocarriers (NCs) is a very promising approach for development of nanomedicine. Modern drug encapsulation methods allow efficient loading of drug molecules inside the NCs thereby reducing systemic toxicity associated with drugs.
Kumari, Avnesh   +3 more
openaire   +3 more sources

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