Results 41 to 50 of about 6,817,458 (407)
Intranasal drug delivery: opportunities and toxicologic challenges during drug development
Drug Delivery and Translational Research, 2021 Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has increased. This review article summarises information on intranasal administration for local and systemic delivery, as well as for CNS indications.
Lea-Adriana Keller +2 more
semanticscholar +1 more source
Advances in Chitosan-Based Nanoparticles for Drug Delivery
International Journal of Molecular Sciences, 2021 Nanoparticles (NPs) have an outstanding position in pharmaceutical, biological, and medical disciplines. Polymeric NPs based on chitosan (CS) can act as excellent drug carriers because of some intrinsic beneficial properties including biocompatibility ...
V. Mikušová, P. Mikuš
semanticscholar +1 more source
Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion
, 2020 Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena +4 more
core +1 more source
Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading. [PDF]
, 2017 Oral delivery of therapeutics is the preferred route for systemic drug administration due to ease of access and improved patient compliance. However, many therapeutics suffer from low oral bioavailability due to low pH and enzymatic conditions, poor ...
Bogdanoff, Derek B +6 more
core +1 more source
Journal for ImmunoTherapy of Cancer, 2021 Background Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus ...
Alessandra Lopes +8 more
doaj +1 more source
A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope [PDF]
, 2016 This paper reports a novel medication release and delivery mechanism as part of a next generation wireless capsule endoscope (WCE) for targeted drug delivery.
Constandinou, TG, Woods, S
core +2 more sources
Advances in oligonucleotide drug delivery
Nature reviews. Drug discovery, 2020 Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these
T. Roberts, R. Langer, M. Wood
semanticscholar +1 more source
Bioengineering & Translational Medicine, 2023 Ionic liquids (ILs) attract more and more interests in improving drug transport across membrane, including transdermal, nasal, and oral delivery. However, some drawbacks of ILs impede the application in oral drug delivery, such as rapid precipitation of ...
Kaiheng Liu +9 more
doaj +1 more source
Lipid Nanoparticles for Drug Delivery
Advanced NanoBiomed Research, 2021 Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu +5 more
semanticscholar +1 more source
The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]
, 2019 Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah +42 more
core +2 more sources