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Advances in drug delivery systems for the management of gout and hyperuricemia. [PDF]
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American Journal of Health-System Pharmacy, 1991
New and emerging drug delivery systems for traditional drugs and the products of biotechnology are discussed, and the role of the pharmacist in ensuring the appropriate use of these systems is outlined. Advantages of advanced drug delivery systems over traditional systems are the ability to deliver a drug more selectively to a specific site; easier ...
D H, Robinson, J W, Mauger
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New and emerging drug delivery systems for traditional drugs and the products of biotechnology are discussed, and the role of the pharmacist in ensuring the appropriate use of these systems is outlined. Advantages of advanced drug delivery systems over traditional systems are the ability to deliver a drug more selectively to a specific site; easier ...
D H, Robinson, J W, Mauger
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Pain Practice, 2006
Abstract: Intrathecal drug delivery (IDD) is a proven and effective treatment alternative in carefully selected patients with chronic pain that cannot be controlled by a well‐tailored drug regime and/or spinal cord stimulation (SCS), and may be specifically trialed in patients who fail to respond to SCS.
Serdar, Erdine, José, De Andrés
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Abstract: Intrathecal drug delivery (IDD) is a proven and effective treatment alternative in carefully selected patients with chronic pain that cannot be controlled by a well‐tailored drug regime and/or spinal cord stimulation (SCS), and may be specifically trialed in patients who fail to respond to SCS.
Serdar, Erdine, José, De Andrés
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Paclitaxel drug delivery systems
Expert Opinion on Drug Delivery, 2013Paclitaxel (PTX) is one of the most effective broad-spectrum chemotherapeutic agents in the treatment of cancers. However, its clinical application has been limited due to its poor water solubility. Its current clinical administration uses the adjuvant of serious side effects and has undesired pharmacokinetics and biodistribution.
Zhiping, Zhang, Lin, Mei, Si-Shen, Feng
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Skeletal drug delivery systems
International Journal of Pharmaceutics, 2000Selective drug delivery to any organ becomes very important in certain diseases and clinical manifestations, especially when the drug affects other exposed tissues adversely. The importance of selective drug action is still further increased when the affected part is poorly perfused.
A K, Jain, R, Panchagnula
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2005
Drugs, in the majority of cases, are toxic at high doses however, they must be present in the circulation for a time sufficient to reach therapeutically useful results. This is commonly achieved by repeated drug administrations, which give rise to peak and valley drug concentration. Such a method of administration has two disadvantages: on the one hand
VERONESE, FRANCESCO, CALICETI, PAOLO
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Drugs, in the majority of cases, are toxic at high doses however, they must be present in the circulation for a time sufficient to reach therapeutically useful results. This is commonly achieved by repeated drug administrations, which give rise to peak and valley drug concentration. Such a method of administration has two disadvantages: on the one hand
VERONESE, FRANCESCO, CALICETI, PAOLO
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Gastroretentive drug delivery systems
Expert Opinion on Drug Delivery, 2006A controlled drug delivery system with prolonged residence time in the stomach is of particular interest for drugs that i) are locally active in the stomach, ii) have an absorption window in the stomach or in the upper small intestine, iii) are unstable in the intestinal or colonic environment, or iv) exhibit low solubility at high pH values.
Alexander, Streubel +2 more
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