Results 271 to 280 of about 464,584 (319)
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Buccal Drug Delivery System-A Novel Drug Delivery System
Research Journal of Science and Technology, 2016Buccal delivery is defined as drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and erratic oral absorption.
Debjit Bhowmik +2 more
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Soft Matter, 2006
This brief review aims at providing some illustrative examples on the use of soft drug delivery systems formed by surfactants, polymers, and lipids. Such delivery systems are discussed and exemplified regarding both more traditional soft drug delivery systems such as micelles, liquid crystalline phases, liposomes and polymer gels, as well as more novel
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This brief review aims at providing some illustrative examples on the use of soft drug delivery systems formed by surfactants, polymers, and lipids. Such delivery systems are discussed and exemplified regarding both more traditional soft drug delivery systems such as micelles, liquid crystalline phases, liposomes and polymer gels, as well as more novel
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Drug delivery to the nervous system
Trends in Biotechnology, 1997Delivery of drugs to the nervous system remains a challenge despite advances in our understanding of the mechanisms involved in the development of neurodegenerative disorders and the actions of neuroactive agents. Drug accessibility to the central nervous system is limited by the blood-brain barrier; although the peripheral nervous system is more ...
D, Maysinger, A, Morinville
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Implantable Drug-Delivery Systems
Scientific American, 1979Implantable drug-delivery systems are being developed to release drugs to the bloodstream continuously as well as free patients from being hospitalized to receive intravenous infusions or frequent injections. One technique is implantation of a pellet in the subcutaneous tissue so the pellet may be released by erosion.
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Bioinspired drug delivery systems
Current Opinion in Biotechnology, 2013The way Nature designs, processes and assembles molecular building blocks to fabricate high performance materials with a minimum of resources is a suitable model for the design of drug delivery systems (DDS) with advanced functionalities. Bioinspired preparation methods that involve the use of superhydrophobic surfaces, layer-by-layer assembly or ...
Carmen, Alvarez-Lorenzo +1 more
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Schizophrenia and Drug Delivery Systems
Journal of Drug Targeting, 2000Schizophrenia is a severe non-curable illness of the brain with serious consequences if not properly treated and kept under control. Antipsychotic drugs have revolutionised the therapy and management of schizophrenia. However, patient compliance rates are notoriously poor due to the nature of the disease and troublesome side-effects, and are major ...
Y H, Cheng, L, Illum, S S, Davis
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Nanocapsules as Drug Delivery Systems
The International Journal of Artificial Organs, 2005Dispersed polymer nanocapsules can serve as nano-sized drug carriers to achieve controlled release as well as efficient drug targeting. The dispersion stability and the primary physiological response are mainly determined by the type of the surfactant and the nature of the outer coating.
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Drug Delivery Systems - An Overview
2008This is an overview of drug delivery systems (DDS), starting with various routes of drug administration. Various drug formulations, as well as devices used for drug delivery and targeted drug delivery, are then described. Delivery of proteins and peptides presents special challenges.
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Gastroretentive drug delivery systems
Expert Opinion on Drug Delivery, 2006A controlled drug delivery system with prolonged residence time in the stomach is of particular interest for drugs that i) are locally active in the stomach, ii) have an absorption window in the stomach or in the upper small intestine, iii) are unstable in the intestinal or colonic environment, or iv) exhibit low solubility at high pH values.
Alexander, Streubel +2 more
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Skeletal drug delivery systems
International Journal of Pharmaceutics, 2000Selective drug delivery to any organ becomes very important in certain diseases and clinical manifestations, especially when the drug affects other exposed tissues adversely. The importance of selective drug action is still further increased when the affected part is poorly perfused.
A K, Jain, R, Panchagnula
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