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Mucoadhesive Drug Delivery Systems
2009The uptake of drugs is often limited by the short contact time between the formulation and the absorption membrane and by a fast washout. Using mucoadhesive polymers, however, the residence time of the dosage form on the mucosa can be significantly increased.
Juliane, Hombach +1 more
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Bioinspired drug delivery systems
Current Opinion in Biotechnology, 2013The way Nature designs, processes and assembles molecular building blocks to fabricate high performance materials with a minimum of resources is a suitable model for the design of drug delivery systems (DDS) with advanced functionalities. Bioinspired preparation methods that involve the use of superhydrophobic surfaces, layer-by-layer assembly or ...
Carmen, Alvarez-Lorenzo +1 more
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Journal of Aerosol Medicine, 1994
Nebulizers, both jet and ultrasonic, were originally designed to convert a liquid solution into an aerosol. During recent years suspensions for nebulization have been developed and nebulized with the available devices. In-vitro comparisons of drug output from jet and ultrasonic nebulizers have shown significant differences between solutions and ...
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Nebulizers, both jet and ultrasonic, were originally designed to convert a liquid solution into an aerosol. During recent years suspensions for nebulization have been developed and nebulized with the available devices. In-vitro comparisons of drug output from jet and ultrasonic nebulizers have shown significant differences between solutions and ...
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Drug Delivery Systems. 6. Transdermal Drug Delivery
The Journal of Clinical Pharmacology, 1991Transdermal drug delivery system has been in existence for a long time. In the past, the most commonly applied systems were topically applied creams and ointments for dermatological disorders. The occurrence of systemic side‐effects with some of these formulations is indicative of absorption through the skin.
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Drug Delivery Systems 5A. Oral Drug Delivery
The Journal of Clinical Pharmacology, 1991The two main advantages of controlled drug delivery systems are: maintenance of therapeutically optimum drug concentrations in the plasma through zero‐order release without significant fluctuations; and elimination of the need for frequent single dose administrations.
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Pulsatile Drug-Delivery Systems
Critical Reviews in Therapeutic Drug Carrier Systems, 2001Delivery systems with a pulsatile-release pattern are receiving increasing interest for the development of drugs for which conventional controlled drug-release systems with a continuous release are not ideal. These drugs often have a high first-pass effect or special chronopharmacological needs.
T, Bussemer, I, Otto, R, Bodmeier
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Soft Matter, 2006
This brief review aims at providing some illustrative examples on the use of soft drug delivery systems formed by surfactants, polymers, and lipids. Such delivery systems are discussed and exemplified regarding both more traditional soft drug delivery systems such as micelles, liquid crystalline phases, liposomes and polymer gels, as well as more novel
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This brief review aims at providing some illustrative examples on the use of soft drug delivery systems formed by surfactants, polymers, and lipids. Such delivery systems are discussed and exemplified regarding both more traditional soft drug delivery systems such as micelles, liquid crystalline phases, liposomes and polymer gels, as well as more novel
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Microparticulate drug delivery systems
1999Chitosan was proposed as a drug carrier for mucosal administration in ocular, buccal, nasal, gastroenteric and vaginal-uterine therapies based on its bioadhesive properties and biodegradability in vivo under the action of hydrolases. Examples are the delivery of acyclovir via ocular administration, and the delivery of 5-aminosalicylic acid to the colon.
GENTA, IDA +5 more
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Buccal Drug Delivery System-A Novel Drug Delivery System
Research Journal of Science and Technology, 2016Buccal delivery is defined as drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and erratic oral absorption.
Debjit Bhowmik +2 more
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Bioresponsive drug delivery systems
Drug Discovery TodayIn this review, we highlight the potential of stimuli-responsive drug delivery systems (DDSs) to revolutionize healthcare. Through examining pH, temperature, enzyme, and redox responsiveness, the presented case studies highlight the precision and enhanced therapeutic outcomes achievable with these innovative systems.
Seyed Ebrahim, Alavi +4 more
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