Results 81 to 90 of about 466,787 (269)

Supramolecular Nano‐Grid Platform to Load and Deliver Liposomes and Exosomes

Small Structures
In general, carriers are designed to deliver pharmaceutical (featuring small drug‐molecules) and biopharmaceutical (featuring large‐molecule drugs, e.g., antibodies, proteins, etc.) active ingredients and platform that is capable of transporting ...
Jing Li, Wuzhen Ma, Xiaohong Ren, Tao Guo, Boyang Yang, Chenxi Huang, Ting Xiong, Yuhua Guo, Zeru Li, Siwen Wang, Bingqian Jia, Shujun Wang, Li Wu, Jiwen Zhang   +13 more
doaj   +1 more source

Neutrophil-mimicking therapeutic nanoparticles for targeted chemotherapy of pancreatic carcinoma

Acta Pharmaceutica Sinica B, 2019
Due to the critical correlation between inflammation and carcinogenesis, a therapeutic candidate with anti-inflammatory activity may find application in cancer therapy.
Xi Cao, Ying Hu, Shi Luo, Yuejing Wang, Tao Gong, Xun Sun, Yao Fu, Zhirong Zhang   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Current Status of Drug Delivery Systems for Antifungal Drugs [PDF]

, 2012
The number of deep-seated mycosis cases is increasing rapidly along with the extreme advanced technology and highly sophisticated treatment. High mortality of deep-seated mycosis is critical concern, and an appropriate strategy and usage of antifungals ...
河野, 茂, 泉川, 公一
core   +1 more source

Hydrogels as Drug Delivery Systems: A Review of Current Characterization and Evaluation Techniques [PDF]

, 2020
Owing to their tunable properties, controllable degradation, and ability to protect labile drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a lack of standardized methodologies used to characterize and evaluate drug
Christoph Meinert, Dietmar W. Hutmacher, Margaux Vigata, Nathalie Bock   +3 more
core   +1 more source

Preparation and evaluation of a phospholipid-based injectable gel for the long term delivery of leuprolide acetaterrh

Acta Pharmaceutica Sinica B, 2016
A phospholipid-based injectable gel was developed for the sustained delivery of leuprolide acetate (LA). The gel system was prepared using biocompatible materials (SPME), including soya phosphatidyl choline (SPC), medium chain triglyceride (MCT) and ...
Danhong Long, Tao Gong, Zhirong Zhang, Rui Ding, Yao Fu   +4 more
doaj   +1 more source

A magnetism/laser-auxiliary cascaded drug delivery to pulmonary carcinoma

Acta Pharmaceutica Sinica B, 2020
Although high-efficiency targeted delivery is investigated for years, the efficiency of tumor targeting seems still a hard core to smash. To overcome this problem, we design a three-step delivery strategy based on streptavidin–biotin interaction with the
Jialiang Lin, Qingqing Yin, Binlong Chen, Haoran Zhang, Dong Mei, Jijun Fu, Bing He, Hua Zhang, Wenbing Dai, Xueqing Wang, Yiguang Wang, Qiang Zhang   +11 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?" [PDF]

, 2009
Chinese medicine could serve as a source of inspiration for drug development. Using systems biology in combination with reverse pharmacology is a novel way for the discovery of novel biological active compounds and targets as well as for proving the ...
Greef, J., de, Gilissen, L.J.W.J., Advanced drug delivery systems/drug targeting, Witkamp, R.F., Dep Farmaceutische wetenschappen, Crommelin, D., Danhof, M., Crommelin, D.J.A., van der Greef, H.J., Verpoorte, R., Gilissen, L.J., Schuitmaker, H., de Greef, J.   +12 more
core   +1 more source

Targeted Delivery of Arctigenin Using Sialic Acid Conjugate-Modified Liposomes for the Treatment of Breast Cancer

Molecules
Arctigenin (ATG) is a broad-spectrum antitumor drug with an excellent inhibitory effect on malignant tumors such as breast cancer, glioblastoma, liver cancer, and colon cancer.
Shunfang Liu, Yaozhen He, Minding Feng, Yongtong Huang, Wenhao Wu, Jiu Wang   +5 more
doaj   +1 more source