Results 91 to 100 of about 464,584 (319)
Local Drug Delivery in Bladder Cancer: Advances of Nano/Micro/Macro-Scale Drug Delivery Systems
, 2023 Treatment of bladder cancer remains a critical unmet need and requires advanced approaches, particularly the development of local drug delivery systems. The physiology of the urinary bladder causes the main difficulties in the local treatment of bladder ...
Irina Marchenko, Daria Trushina
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A Painless Drug Delivery System / Transedermal Drug Delivery System
International Journal of Advanced Research in Science, Communication and TechnologyTransdermal drug delivery systems (TDDS) represent an innovative and painless approach for administering therapeutic agents through the skin. Unlike conventional oral or injectable routes, transdermal patches bypass first-pass metabolism, provide controlled and sustained drug release, and enhance patient compliance by reducing pain and discomfort ...
null Supekar Rohini K. +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Polysaccharide drug delivery systems based on pectin and chitosan
, 2010 Chitosans and pectins are natural polysaccharides which show great potential in drug delivery systems. Chitosans are a family of strongly polycationic derivatives of poly-N-acetyl-D-glucosamine.
Kok, M. S. +3 more
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Strategic design of extracellular vesicle drug delivery systems [PDF]
, 2018 Extracellular vesicles (EVs), sub-micron vectors used in intercellular communication, have demonstrated great promise as natural drug delivery systems. Recent reports have detailed impressive in vivo results from the administration of EVs pre-loaded with
Armstrong, JP, Stevens, MM
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Handbook of non-invasive drug delivery systems : science and technology /
, 2009 With the improvements in formulation science and certain transdermal delivery technologies, the non-invasive mode of drug delivery is now ready to compete with traditional methods of oral and injectible routes of drug delivery.
Kulkarni, Vitthal S.
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Structural and functional characterization of self-assembling amphiphilic oligopeptides
, 2009 The aim of this thesis was to design amphiphilic peptides that self-assemble into supramolecular structures, like nano-sized vesicles that can be of use for drug delivery purposes.
Dep Farmaceutische wetenschappen +2 more
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Computational modelling of drug delivery to solid tumour: Understanding the interplay between chemotherapeutics and biological system for optimised delivery systems [PDF]
, 2018 Drug delivery to solid tumour involves multiple physiological, biochemical and biophysical processes taking place across a wide range of length and time scales.
Xu, Xiao Yun, Zhan, Wenbo, Alamer, Moath
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