A Conceptual Translational Bench-to-Bedside Cardiac Safety Framework for Predicting Drug-Induced QT Interval Prolongation from Molecular Structure to Clinical Data. [PDF]
Int J Mol SciSips F +17 more
europepmc +1 more source
Bio‐Inspired Artificial Ionic Mechanoreceptor
Advanced Functional Materials, EarlyView.A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari +4 more
wiley +1 more source
Population Pharmacokinetic, Exposure-Response Efficacy and Safety Analyses of Favezelimab in Patients With Solid Tumors. [PDF]
Clin Transl SciGaurav M +4 more
europepmc +1 more source
Central and peripheral changes in oxygenation and temperatures induced by intravenous nicotine in freely moving male rats. [PDF]
Brain ResArce A, Limiac F, Kiyatkin EA.
europepmc +1 more source
Hierarchical Composite Endpoints for Dose Optimization in Early Phase Oncology Trials. [PDF]
Pharm StatWu Y, Guo X, Li R, Le Corre C.
europepmc +1 more source
Cardiac Vagal Decoupling in Canine Anesthesia: A Physiological Concept for Graded Vasopressor Titration. [PDF]
Vet SciNagahama S.
europepmc +1 more source
Equipotent Doses and ED95 Extrapolation: Methodological Concerns in Trials of Ciprofol-Esketamine/Sufentanil for Elderly ESD [Letter]. [PDF]
Drug Des Devel TherLi L, Zhang Z, Wang Z, Li C.
europepmc +1 more source
Dose-Response Meta-Analysis: A Quantitative Perspective on Rheumatic Diseases. [PDF]
Int J Rheum DisLei Y, Tang T, Du A, Xu L, Tung WT.
europepmc +1 more source