Results 221 to 230 of about 171,263 (267)

The Scientific Basis of Drug-Drug Interactions: Mechanism and Preclinical Evaluation

Drug Information Journal, 1998
Pharmacokinetic drug-drug interactions (PDDI), in which the pharmacokinetic clearance of one drug is altered by a coadministered drug, can be divided mechanistically into two general categories: 1. Inhibitory PDDI—the inhibition of the metabolic clearance of one drug by a coadministered drug, and 2.
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Preclinical Evaluation of Cudetaxestat for Potential Drug-Drug Interactions

B36. SPECTRUM OF FIBROTIC INTERSTITIAL LUNG DISEASES, 2022
W. Yu, R. Rajagopalan, J. Lin, P. Ibrahim   +3 more
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ChemInform Abstract: Drug Safety Evaluation at the Preclinical Stage

ChemInform, 1991
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Treatment of schizophrenia: A clinical and preclinical evaluation of neuroleptic drugs

Pharmacology & Therapeutics, 1993
Forty years after the first clinical report on the effectiveness of chlorpromazine in psychiatric patients, neuroleptic drugs are still the most widely used drugs in the treatment of schizophrenia. Indeed, there are no other drugs which have proven to be as effective in the treatment of this severe psychiatric disorder.
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Preclinical evaluation of drug effects on testicular functions

Pharmacology & Therapeutics, 1979
F, Neumann, B, Schenck
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Preclinical Evaluation of Neuraxial Drugs for Safety

2023
Tony L. Yaksh, Robert B. Boyd, Orion Paul Keifer   +2 more
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Evaluation of Antiseptic Drug Candidate Pyridosept in Preclinical in Vitro Studies

Current Medicinal Chemistry
Introduction: This work provides preclinical in vitro studies of an innovative antimicrobial agent named pyridosept, belonging to the quaternary bis-ammonium salts and synthesized on the base of pyridoxine. Since the wide spread of pathogens with tolerance to both antibiotics and antiseptics challenges the ...
Renata Kazakova, Alfiya Iksanova, Mariya Agafonova, Anna Lubina, Elena Bulatova, Elena Nikitina, Svetlana Lisovskaya, Airat Kayumov, Oxana Bondar, Albina Malanyeva, Olga Vasileva, Marina Zeldi, Alina Gatina, Sergei Koshkin, Natalia Komcharova, Yulia Konyakhina, Kseniia Titova, Aleksandr Sergeev, Sergey Sapozhnikov, Nikita Shtyrlin, Yurii Shtyrlin   +20 more
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Shanu Modi   +2 more
exaly  

Human malignant melanoma: preclinical and clinical drug evaluation.

Behring Institute Mitteilungen, 1984
A panel of 17 melanoma xenograft lines was exposed to various DNA reactive agents. Growth delay values were calculated from tumor volume responses of xenograft bearing mice and correlated with donor patient's response as determined by standard clinical criteria.
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Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly