Results 31 to 40 of about 7,204,824 (312)
BiomimeticsRadiation-induced skin injury (RISI) is one of the most common complications of radiotherapy, severely compromising patients’ quality of life. However, no standardized treatment has yet been established.
Yinhui Wang +7 more
doaj +1 more source
BMC Complementary Medicine and Therapies, 2021 Background The dysfunction of the thyroid gland is a common medical condition. Nowadays, patients frequently use medicinal herbs as complementary or alternative options to conventional drug treatments. These patients may benefit from treatment of thyroid
Lubov V. Krepkova +7 more
doaj +1 more source
Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987
, 2019 The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core +1 more source
Characterization of phototoxicity reactions in human and animal skin models [PDF]
, 2013 Phototoxicity is a relatively common phenomenon and is an adverse effect of some systemic drugs. A large number of pharmaceutical drug substances are known to carry the potential to elicit a phototoxic response (Moore 2002, Ferguson 2002). Reported cases
Boudon, Stéphanie
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Molecules, 2020 Bedaquiline is a novel drug approved in 2012 by the FDA for treatment of drug-resistant tuberculosis (TB). Although it shows high efficacy towards drug-resistant forms of TB, its use has been limited by the potential for significant side effects.
Peter J. Choi +8 more
doaj +1 more source
Preclinical evaluation of drugs to block inflammation-driven preterm birth [PDF]
Innate Immunity, 2016 Intrauterine inflammation, the major cause of early preterm birth, can have microbial and sterile aetiologies. We assessed in a Transwell model the anti-inflammatory efficacies of five drugs on human extraplacental membranes delivered after preterm spontaneous labour (30–34 wk). Drugs [TPCA1 (IKKβ inhibitor), 5 z-7-oxozeaenol (OxZ,
Demelza J, Ireland +7 more
openaire +2 more sources
Prediction of human drug clearance and anticipation of clinical drug-drug interaction potential from in vitro drug transport studies [PDF]
, 2014 A major concern in drug development is the characterization of new molecular entities (NMEs) with respect to their safety and efficacy. Both factors are determined by the drug’s exposure within the body which itself is affected by drug clearance ...
Kunze, Annett
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Complement activation as a bioequivalence issue relevant to the development of generic liposomes and other nanoparticulate drugs [PDF]
, 2015 Liposomes are known to activate the complement (C) system, which can lead in vivo to a hypersensitivity syndrome called C activation-related pseudoallergy (CARPA). CARPA has been getting increasing attention as a safety risk of i.v.
Pharmaceutics +3 more
core +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source