Results 91 to 100 of about 1,388,675 (309)

Evaluation of Pharmacokinetic Drug–Drug Interactions: A Review of the Mechanisms, In Vitro and In Silico Approaches

open access: yes, 2021
Pharmacokinetic drug–drug interactions (DDIs) occur when a drug alters the absorption, transport, distribution, metabolism or excretion of a co-administered agent.
Yaru Peng, Feifan Xie, Zeneng Cheng
core   +1 more source

Bioinspired microfluidic approach for cell-based drug evaluation

open access: yes, 2011
Cell-based drug evaluation is critical for the process of drug screening and drug discovery ...Cell-based drug evaluation is critical for the process of drug screening and drug discovery ..
秦建华, JianhuaQin
core  

Application of RNAi to Genomic Drug Target Validation in Schistosomes. [PDF]

open access: yes, 2015
Concerns over the possibility of resistance developing to praziquantel (PZQ), has stimulated efforts to develop new drugs for schistosomiasis. In addition to the development of improved whole organism screens, the success of RNA interference (RNAi) in ...
Bickle, Quentin D   +29 more
core   +1 more source

The Role of Oral Controlled Release Matrix Tablets in Drug Delivery Systems [PDF]

open access: yes, 2012
Formulations that are able to control the release of drug have become an integral part of the pharmaceutical industry. In particular oral drug delivery has been the focus of pharmaceutical research for many years.
Raja, Shaista   +11 more
core   +1 more source

Evaluation of Rongo Atea: Alcohol and Other Drug Treatment Centre for Adolescents

open access: yes, 2010
Rongo Ātea is a residential abstinence-based Kaupapa Māori alcohol and other drug programme accommodating youth between the ages of 13 and 17. This evaluation investigates the role that staff play at Rongo Ātea along with a number of other factors ...
Paki, Helen Mary
core  

Reform and Development of Rare Diseases Drug Evaluation and Approval in China

open access: yes罕见病研究
Rare diseases have a significant and profound impact on society, the economy, and the healthcare system. The path to developing drugs for rare diseases is particularly arduous. Due to the small number of patients and limited market demand, pharmaceutical
HUANG Guo   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Evaluation of SWSLHD Aboriginal Outreach Drug & Alcohol Clinics in Airds and Bowral: Overarching Report

open access: yes, 2018
Aboriginal people experience a disproportionate amount of the harms associated with use of substances such as alcohol, illicit drugs and pharmaceuticals. Treatment is one component of a multifaceted approach to reducing the impact of drug-related harm on
Blignault, Ilse (R18379)
core  

Guide to evaluating drug prevention projects in Victoria. [PDF]

open access: yes, 2002
This guide provides information on what an evaluation is and the key steps in doing an evaluation. This guide will assist in designing and evaluating individual drug prevention projects.

core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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