Results 81 to 90 of about 1,388,675 (309)

New South Wales drug court evaluation: Cost-effectiveness, CHERE Project Report 17a [PDF]

In this report we examine an issue central to the creation of the NSW Drug Court: namely its cost-effectiveness, compared with conventional sanctions, in reducing drug-related crime.
Marion Haas, Marian Shanahan, Don Weatherburn, Shuling Chen, Bronwyn Lind, Emily Lancsar   +5 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Drug Court Process Evaluation Report, February 2008

, 2008
The Iowa Consortium for Substance Abuse Research and Evaluation conducted a process evaluation in 2007 on the seven adult and juvenile drug courts existing in Iowa in 2003.

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Cardiac Adverse Events in Patients Receiving Immune Checkpoint Inhibitors in the Adjuvant Setting: An FDA Pooled Analysis

Annals of Noninvasive Electrocardiology
Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment. By releasing blocks (checkpoints) on the immune system, they elicit powerful antitumor effects.
Asma Dilawari, Mori J. Krantz, Ilynn Bulatao, Hee‐Koung Joeng, Marc Neilson, Suparna Wedam, Xin Gao, Mallorie H. Fiero, Abhilasha Nair, Marc Theoret, Laleh Amiri‐Kordestani   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

FDA’s implementation of knowledge-aided assessment and structured application for manufacturing assessment of non-sterile solid oral dosage form drug products

AAPS Open
The Knowledge-Aided Assessment and Structured Application (KASA) is an initiative led by the FDA’s Center for Drug Evaluation and Research (CDER) which is launched within CDER’s Office of Pharmaceutical Quality (OPQ). It is a platform designed to conduct
Zhouxi Wang, Jingbo Xiao, Daniel Obrzut, Stelios Tsinontides, Rakhi Shah   +4 more
doaj   +1 more source

Introduction to drug utilization research

, 2003
Prepared by the WHO Collaborating Centre for Drug Statistics Methodology, the WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services, and the International Working Group for Drug Statistics Methodology48 p.Korean ...
WHO International Working Group for Drug Statistics Methodology, WHO Collaborating Centre for Drug Statistics Methodology, WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services   +2 more
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10 key findings related to the impact of Toronto’s drug checking service.

, 2023
Toronto's Drug Checking Service is a free and anonymous public health service that aims to reduce the harms associated with substance use and, specifically, to prevent overdose by uncovering the toxicity and potency of the unregulated drug ...
Thompson, H, Werb, D, McDonald, K
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Taking stock of half a decade of drug policy - an evaluation of UNGASS implementation. [PDF]

, 2021
April 2021 marks the five-year anniversary of the 2016 United Nations General Assembly Special Session (UNGASS) on drugs. This report aims to take stock of progress made on the implementation of the operational recommendations included in the UNGASS ...
Cots Fernández, Adria, Putri, Dania, Nougier, Marie   +2 more
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Enhanced drug treatment service evaluation report

, 2023
This is the report of a service evaluation of the Enhanced Drug Treatment Service (EDTS), which is a part of Glasgow City Alcohol and Drug Recovery Services (GADRS).
Carter, Daniel, Dargan, Stephanie, Priyadarshi, Saket   +2 more
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