Results 1 to 10 of about 218,829 (211)

High occurrence of simultaneous multiple-drug hypersensitivity syndrome induced by first-line anti-tuberculosis drugs [PDF]

open access: goldWorld Allergy Organization Journal, 2021
Background: Multiple drug hypersensitivity syndrome (MDHS) results in treatment delay or failure and often results in severe drug hypersensitivity reactions.
Da Woon Sim   +3 more
doaj   +2 more sources

Drug hypersensitivity in drug-resistant tuberculosis [PDF]

open access: yesWorld Allergy Organization Journal, 2023
Objective: To evaluate drug resıstant tuberculosis patients who developed drug hypersensitivity to antituberculosis drug. Methods: This was a retrospective study.
Zeynep Yegin Katran, MD   +8 more
doaj   +2 more sources

Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators [PDF]

open access: yesBiomedicines, 2023
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu   +3 more
doaj   +2 more sources

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

open access: yesFrontiers in Immunology, 2021
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases.
Yun-Shiuan Olivia Hsu   +43 more
doaj   +1 more source

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

open access: yesFrontiers in Pharmacology, 2022
Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS).
Chuang-Wei Wang   +42 more
doaj   +1 more source

Profile of Drug Hypersensitivity Patients Hospitalized in Dr. Soetomo Hospital, Surabaya, Indonesia: Preliminary Data of 6 Months Observation

open access: yesFolia Medica Indonesiana, 2021
Drug hypersensitivity is defined as an untoward response to medication which is noxious and unintended, and which occurs at doses normally used in human either for the prophylaxis, diagnosis, or therapy of disease or for the modification of physiological
Nur Moya Isyroqiyyah   +2 more
doaj   +1 more source

Hypersensitivity reactions to small molecule drugs

open access: yesFrontiers in Immunology, 2022
Drug hypersensitivity reactions induced by small molecule drugs encompass a broad spectrum of adverse drug reactions with heterogeneous clinical presentations and mechanisms.
Jiayin Han   +6 more
doaj   +1 more source

Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults [PDF]

open access: yes, 2017
Background: Drug hypersensitivity is defined as any unfavorable reaction that occurs after the administration of any drug. It may or may not be mediated by the involvement of the immune system.
BEDOLLA BARAJAS, MARTIN   +9 more
core   +1 more source

Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care [PDF]

open access: yes, 2015
Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 ...
Bonczkowski, Pawel   +18 more
core   +7 more sources

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