Results 1 to 10 of about 6,456,703 (287)

Drug hypersensitivity in drug-resistant tuberculosis

World Allergy Organization Journal, 2023
Objective: To evaluate drug resıstant tuberculosis patients who developed drug hypersensitivity to antituberculosis drug. Methods: This was a retrospective study.
Zeynep Yegin Katran, MD, İsmet Bulut, MD, Aylin Babalık, MD, Metin Keren, MD, Fatma Merve Tepetam, MD, Selver Seda Mersin, MD, Cihan Örçen, MD, Tuğçe Yakut, MD, Dilek Yavuz, MD   +8 more
doaj   +4 more sources

Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators

Biomedicines, 2023
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu, Wan-Chun Chang, Shih-Cheng Pao, Shuen-Iu Hung   +3 more
doaj   +2 more sources

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

Frontiers in Immunology, 2021
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases.
Yun-Shiuan Olivia Hsu, Yun-Shiuan Olivia Hsu, Kun-Lin Lu, Kun-Lin Lu, Kun-Lin Lu, Kun-Lin Lu, Yun Fu, Yun Fu, Yun Fu, Yun Fu, Chuang-Wei Wang, Chuang-Wei Wang, Chun-Wei Lu, Chun-Wei Lu, Chun-Wei Lu, Chun-Wei Lu, Yu-Fen Lin, Yu-Fen Lin, Wen-Cheng Chang, Wen-Cheng Chang, Wen-Cheng Chang, Kun-Yun Yeh, Kun-Yun Yeh, Shuen-Iu Hung, Shuen-Iu Hung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen   +43 more
doaj   +2 more sources

Drug hypersensitivity

Acta Clinica Belgica, 2009
Drug hypersensitivity represents an immune-mediated reaction to a drug. Although several drug hypersensitivity reactions are confined to the skin and rather mild, some may be life threatening and also involve further organs such as liver, kidney and bone
Yawalkar, N, Yawalkar N
core   +6 more sources

Recognizing Drug Hypersensitivity in Pigmented Skin

Immunology and allergy clinics of North America, 2022
The imagery of pigmented skin is underrepresented in teaching materials such as textbooks, journals, and online references, and this has resulted in poorer diagnostic and management outcomes of skin pathology, including delayed cutaneous drug ...
R. Lehloenya, E. Phillips, H. Pasieka, J. Peter   +3 more
semanticscholar   +2 more sources

Multiple Drug Hypersensitivity Syndrome in a Large Database

Journal of Allergy and Clinical Immunology: in Practice, 2020
BACKGROUND Multiple drug hypersensitivity syndrome (MDH) is defined as confirmed drug hypersensitivity (DH) to at least 2 chemically and pharmacologically unrelated drugs.
Pascal Demoly, Anca Chiriac, Quentin Landry   +2 more
exaly   +2 more sources

An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity

Journal of Immunology Research, 2018
Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced ...
Chun-Bing Chen, Riichiro Abe, Ren-You Pan, Chuang-Wei Wang, Shuen-Iu Hung, Yi-Giien Tsai, Wen-Hung Chung   +6 more
doaj   +2 more sources

Hypersensitivity reactions to small molecule drugs

Frontiers in Immunology, 2022
Drug hypersensitivity reactions induced by small molecule drugs encompass a broad spectrum of adverse drug reactions with heterogeneous clinical presentations and mechanisms.
Jiayin Han, Chen Pan, Xuan Tang, Qi Li, Yan Zhu, Yushi Zhang, Aihua Liang   +6 more
doaj   +3 more sources

HLA Associations and Clinical Implications in T-Cell Mediated Drug Hypersensitivity Reactions: An Updated Review [PDF]

Journal of Immunology Research, 2014
T-cell mediated drug hypersensitivity reactions may range from mild rash to severe fatal reactions. Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome ...
Chi-Yuan Cheng, Shih-Chi Su, Chi-Hua Chen, Wei-Li Chen, Shin-Tarng Deng, Wen-Hung Chung   +5 more
doaj   +2 more sources

Multiple Drug Hypersensitivity [PDF]

International Archives of Allergy and Immunology, 2017
Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs.
W. Pichler, Y. Srinoulprasert, J. Yun, O. Hausmann   +3 more
semanticscholar   +3 more sources