Results 101 to 110 of about 3,966,363 (347)

Vancomycin-Induced Stevens-Johnson Syndrome in a Boy Under 2 Years Old: An Early Diagnosis by Granulysin Rapid Test

Frontiers in Pediatrics, 2018
Stevens-Johnson syndrome (SJS) is a life-threatening disease, which is mainly ascribed to drugs, such as sulfonamides and psychoepileptics. In this article, we present a pediatric case of vancomycin-induced SJS and an alternative diagnostic algorithm ...
You-Cheng Lin, You-Cheng Lin, Ji-Nan Sheu, Ji-Nan Sheu, Wen-Hung Chung, Wen-Hung Chung, Ren-You Pan, Chu-Ju Hung, Jen-Jung Cheng, Yu-Ping Hsiao, Yu-Ping Hsiao   +10 more
doaj   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

HLA-DRB1 is associated with cefaclor-induced immediate hypersensitivity

World Allergy Organization Journal
Background: Drug-induced hypersensitivity such as anaphylaxis is an important cause of drug-related morbidity and mortality. Cefaclor is a leading cause of drug induced type I hypersensitivity in Korea, but little is yet known about genetic biomarkers to
So-Young Park, MD, PhD, So Young Park, MD, PhD, Sujin Seo, BS, Hyouk-Soo Kwon, MD, PhD, Seung-Hyun Kim, PhD, Sae-Hoon Kim, MD, PhD, Hye-Kyung Park, MD, PhD, Yoon-Seok Chang, MD, PhD, Cheol-Woo Kim, MD, PhD, Byung Jae Lee, MD, PhD, Hae-Sim Park, MD, PhD, You Sook Cho, MD, PhD, Heung-Bum Oh, PhD, David A. Ostrov, PhD, Sungho Won, PhD, Tae Bum Kim, MD, PhD   +15 more
doaj   +1 more source

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

Advanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye, Xinyi Wu, Jin Liu, Yongmi Guo, Chong Ji, Zhouyue Wang, Di Yang, Min Zhou   +7 more
wiley   +1 more source

Hypersensitivity to chemotherapeutic drugs for the treatment of neoplasms. Literature review

Infusion & Chemotherapy
BACKGROUND. Like any other drug, chemotherapy drugs can cause hypersensitivity reactions and are the third leading cause of drug-induced anaphylaxis deaths in the United States.
S.V. Zaikov, M.A. Lykova, N.A. Hritsova, L.V. Veselovsky   +3 more
doaj   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

Advanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua, Kaiqiang Li, Pengyou Shang, Lina Liu, Jiayu Pan, Bo Zhu, Zichun Hua   +6 more
wiley   +1 more source

The Association of Increased Spontaneous Lymphocyte Transformation in Vitro with Clinical Manifestations of Drug Hypersensitivity [PDF]

, 1967
Fred A. Gill
openalex   +1 more source

Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms

International Archives of Allergy and Immunology, 2016
Drug hypersensitivity reactions (DHR) are clinically and functionally heterogeneous. Different subclassifications based on timing of symptom appearance or type of immune mechanism have been proposed. Here, we show that the mode of action of drugs leading
W. Pichler, O. Hausmann
semanticscholar   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Cefoperazone induced hypersensitivity vasculitis

Indian Journal of Dermatology, 2009
Cefoperazone has been reported to cause vasculitic complications only once before. Here, we report yet another case of hypersensitivity vasculitis associated with cefoperazone.
Katiyar Subodh, Prakash Shivesh
doaj