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Drug Hypersensitivity Syndrome Induced by Meglumine Antimoniate
The American Journal of Tropical Medicine and Hygiene, 2009We report a case of drug hypersensitivity syndrome (drug reaction with eosinophilia and systemic symptoms [DRESS]) induced by parenteral meglumine antimoniate (Glucantime) in a 40-year-old man who traveled to Bolivia and was treated for mucocutaneous leishmaniasis.
Fakhri, Jeddi +5 more
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Cyclosporine Treatment of Drug-Induced Hypersensitivity Syndrome
JAMA Dermatology, 2016Drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is a potentially life-threatening reaction to medications with a mortality rate up to 10%. Standard therapy involves the use of systemic corticosteroids with tapering doses extending up to 9 months after the initial ...
Mark G, Kirchhof +2 more
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Drug‐induced Hypersensitivity Syndrome in a Premature Infant
Pediatric Dermatology, 2005Abstract: Fever, skin reactions, and limb edema because of drug‐induced hypersensitivity have been reported in children because of various drugs, mainly aromatic antiepileptic drugs such as phenytoin, phenobarbital, carbamazepin, and primidone. The skin reactions differ in severity and range from mild maculopapular erythema to exfoliative dermatitis ...
Sule, Yigit +2 more
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Drug-Induced Hypersensitivity Syndrome in Pediatric Patients
Pediatrics, 2001The antiepileptic hypersensitivity syndrome is a severe, multiorgan reaction to oral antiepileptics that manifests as fever, rash, lymphadenopathy, and hepatitis. This same reaction pattern also has been described following administration of a few unrelated medications.
M C, Carroll +3 more
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Drug Eruptions and Hypersensitivity Syndromes
2016Drug eruptions and hypersensitivity reactions are commonly encountered diagnoses in inpatient pediatric dermatology and can range from simple cutaneous eruptions to severe, life-threatening systemic reactions. Although etiology varies by diagnosis, these reactions are most often triggered by medication exposure and/or infectious agents. In this chapter,
Nicole N. Harter, Minnelly Luu
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Antiepileptic Drug-Induced Hypersensitivity Syndrome Reactions
Current Drug Safety, 2006Host dependent idiosyncratic drug reactions, otherwise known as unpredictable type B reactions, are of a major concern in clinical practice and drug development. Hypersensitivity syndrome reactions are idiosyncratic in nature and may be induced by a variety of agents including antiepileptic drugs (AEDs). The AEDs hypersensitivity syndrome is a rare but
Norberto, Krivoy +2 more
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Hypersensitivity syndrome due to 2 anticonvulsant drugs
Contact Dermatitis, 1999Drug‐induced hypersensitivity syndrome is a multiorgan‐system reaction characterized by fever, pleomorphic eruption, lymphadenopathy, eosinophilia, lymphocytosis and hepatitis. We report a drug hypersensitivity syndrome in a 6‐year‐old Tunisian child treated for epileptic absences with sodium valproate and ethosuximide. Imputability of these 2 drugs is
V, Conilleau +4 more
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New aspects of drug‐induced hypersensitivity syndrome
The Journal of Dermatology, 2011AbstractDrug‐induced hypersensitivity syndrome (DIHS) is caused by a limited number of specific drugs and is characterized by late onset, infectious mononucleosis‐like symptoms, and herpesvirus 6 (HHV‐6) reactivation. Recently, the involvement of herpes viruses other than HHV‐6, such as Epstein–Barr virus and cytomegalovirus, has been reported.
Mikiko, Tohyama, Koji, Hashimoto
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[The drug hypersensitivity syndrome or DRESS syndrome to phenobarbital].
Allergie et immunologie, 2001Drug Rash with Eosinophilia and Systemic Symptoms (DRESS syndrome) or the drug hypersensitivity syndrome is a delayed and serious skin disease. It is manifest by a severe skin reaction associated with a severe visceral attack (adenopathy, hepatitis, nephritis, interstitial pneumopathy...) and haematological anomalies (raised hypereosinophilia...).
T, Lachgar, Y, Touil
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