Results 11 to 20 of about 69,415 (156)

Drug-Hypersensitivity Syndrome: Diagnosis and Treatment [PDF]

open access: yesThe Journal of the American College of Clinical Wound Specialists, 2011
Drug-induced hypersensitivity syndrome is a systemic autoimmune disorder that results in mucocutaneous symptoms ranging in severity from mild pruritus to life-threatening skin and mucosal loss, with different nomenclature depending on the severity of the symptoms.
Hamm RL.
exaly   +5 more sources

High occurrence of simultaneous multiple-drug hypersensitivity syndrome induced by first-line anti-tuberculosis drugs [PDF]

open access: yesWorld Allergy Organization Journal, 2021
Background: Multiple drug hypersensitivity syndrome (MDHS) results in treatment delay or failure and often results in severe drug hypersensitivity reactions.
Da Woon Sim   +3 more
doaj   +2 more sources

Multiple Drug Hypersensitivity Syndrome in a Large Database

open access: yesJournal of Allergy and Clinical Immunology: in Practice, 2020
Multiple drug hypersensitivity syndrome (MDHS) is defined as confirmed drug hypersensitivity (DH) to at least 2 chemically and pharmacologically unrelated drugs. Reports of MDHS are scarce and poorly specified, and studies that diagnose MDHS on the basis of positive allergy test results are lacking.To evaluate retrospectively the frequency and ...
Quentin Landry   +2 more
exaly   +5 more sources

Pustular drug hypersensitivity syndrome due to allopurinol.

open access: yesIndian J Pharmacol, 2015
Allopurinol hypersensitivity syndrome (AHS) is a severe drug reaction. It is characterized by rash, fever, and internal organ involvement. It may present in different clinical forms. We present a case of acute generalized exanthematous pustulosis occurring as a manifestation of AHS.
Ben Salem C   +5 more
europepmc   +4 more sources

Vancomycin-associated drug-induced hypersensitivity syndrome [PDF]

open access: yesJournal of the American Academy of Dermatology, 2019
Although hypersensitivity reactions are well characterized for certain medications, vancomycin-associated drug-induced hypersensitivity syndrome (DIHS), or drug reaction with eosinophilia and systemic symptoms (DRESS), has yet to be defined.To better define the clinical phenotype of vancomycin-associated DIHS.A retrospective case series was conducted ...
Lauren M Madigan, Lindy P Fox
exaly   +3 more sources

When allergy strikes the heart: Kounis syndrome and cardiac arrest [PDF]

open access: yesEuropean Journal of Case Reports in Internal Medicine
Introduction: Kounis syndrome is an acute coronary syndrome precipitated by allergic or hypersensitivity reactions and mediated by the release of inflammatory substances that affect the coronary circulation.
Marta Chiara Sircana   +3 more
doaj   +2 more sources

Drug hypersensitivity syndrome

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2011
Drug hypersensitivity syndrome (DHS) is an adverse drug reaction commonly associated with the aromatic antiepileptic drugs (AEDs), viz., phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), lamotrigine, primidone, etc. It can also be caused by other drugs, such as sulfonamides, dapsone, minocycline, gold derivatives, cyclosporine, captopril ...
Kumari, Rashmi   +2 more
  +5 more sources

Profile of Drug Hypersensitivity Patients Hospitalized in Dr. Soetomo Hospital, Surabaya, Indonesia: Preliminary Data of 6 Months Observation

open access: yesFolia Medica Indonesiana, 2021
Drug hypersensitivity is defined as an untoward response to medication which is noxious and unintended, and which occurs at doses normally used in human either for the prophylaxis, diagnosis, or therapy of disease or for the modification of physiological
Nur Moya Isyroqiyyah   +2 more
doaj   +1 more source

The Roles of Immunoregulatory Networks in Severe Drug Hypersensitivity

open access: yesFrontiers in Immunology, 2021
The immunomodulatory effects of regulatory T cells (Tregs) and co-signaling receptors have gained much attention, as they help balance immunogenic and immunotolerant responses that may be disrupted in autoimmune and infectious diseases.
Yun-Shiuan Olivia Hsu   +43 more
doaj   +1 more source

Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators

open access: yesBiomedicines, 2023
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu   +3 more
doaj   +1 more source

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